miRNA pathway alteration in response to non-coding RNA delivery in viral vector-based gene therapy

DA Savenkova, ALA Makarova, IK Shalik… - International Journal of …, 2022 - mdpi.com
Gene therapy is widely used to treat incurable disorders and has become a routine
procedure in clinical practice. Since viruses can exhibit specific tropisms, effectively …

Methyltransferase-like (METTL) 14-mediated N6-methyladenosine modification modulates retinal pigment epithelial (RPE) activity by regulating the methylation of …

L Yin, C Ma, S Hou, X Ma - Bioengineered, 2022 - Taylor & Francis
The expression of METTL14 is significantly reduced in patients with retinitis pigmentosa
(RP). To clarify the significance of the N6-methyladenosine (m6A) RNA modification in RP …

Exosomal miR-4488 and miR-1273g-5p inhibit the epithelial-mesenchymal transition of transforming growth factor β2-mediated retinal pigment epithelial cells by …

H Dong, M Wang, Q Li - Bioengineered, 2021 - Taylor & Francis
Exosomal microRNAs (miRNAs) have been shown to be involved in the regulation of many
disease progression, including proliferative vitreoretinopathy (PVR). However, the roles of …

Effects of resveratrol on autophagy and the expression of inflammasomes in a placental trophoblast oxidative stress model

M Li, X Wu, P An, H Dang, Y Liu, R Liu - Life sciences, 2020 - Elsevier
Objective We aim to investigate whether there is activation of NLRP1 and autophagy in
trophoblast oxidative stress model. Resveratrol was taken to clarify its role in oxidative …

Quantitative phase gradient metrology using diffraction phase microscopy and deep learning

A Venkata Satya Vithin, R Gannavarpu - Journal of the Optical …, 2023 - opg.optica.org
In<? TeX 2pc 0pt?> quantitative phase microscopy, measurement of the phase gradient is
an important problem for biological cell morphological studies. In this paper, we propose a …

[HTML][HTML] Serum miR-4488 as a potential biomarker of lean nonalcoholic fatty liver disease

N Shen, L Tang, Y Qian, J Pan, J Pan… - Annals of …, 2023 - ncbi.nlm.nih.gov
Background In lean individuals, nonalcoholic fatty liver disease (NAFLD) is not a benign
disease, and these patients have long-term morbidity and mortality similar to those of their …

Microarray analysis of small extracellular vesicle‐derived miRNAs involved in oxidative stress of RPE cells

K Mao, X Wu - Oxidative Medicine and Cellular Longevity, 2020 - Wiley Online Library
The aim of this study was to investigate the miRNA profiles of nanosized small extracellular
vesicles (sEVs) from human retinal pigment epithelial (RPE) cells under oxidative damage …

[HTML][HTML] Aspongopus chinensis Dallas induces pro-apoptotic and cell cycle arresting effects in hepatocellular carcinoma cells by modulating miRNA and mRNA …

R Cai, X Chen, S Khan, H Li, J Tan, Y Tian, S Zhao… - Heliyon, 2024 - cell.com
Aspongopus chinensis Dallas is a traditional Chinese medicinal insect with several
anticancer properties can inhibit cancer cell growth, by inhibiting cell division, autophagy …

[PDF][PDF] microRNA-4488 in extracellular vesicles derived from marrow mesenchymal stem cells suppresses ABHD8 to inhibit ovarian cancer progression

L Chang, J Zhou, W Tian, M Chen, R Guo, N Lei - 2020 - pdfs.semanticscholar.org
Background Extracellular vesicle (EV) that delivered microRNAs (miRNAs) have been found
as the important biomarkers participating in the pathological mechanism of ovarian cancer …

[引用][C] Ke Mao

X Wu