Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …

Though only a decade has elapsed since the default network (DN) was first defined as a
large‐scale brain system, recent years have brought great insight into the network's adaptive …

Cognitive aging is often described in the context of loss or decline. Emerging research
suggests that the story is more complex, with older adults showing both losses and gains in …

Cerebellar abnormalities, particularly in Right Crus I (RCrusI), are consistently reported in
autism spectrum disorders (ASD). Although RCrusI is functionally connected with ASD …

Alzheimer disease (AD) originally meant a disorder of early-onset (EOAD;< 65 years of age)
and did not include older patients with “senile dementia.” In fact, the first patient reported …

There is considerable debate whether Alzheimer's disease (AD) originates in basal
forebrain or entorhinal cortex. Here we examined whether longitudinal decreases in basal …

Never before have we experienced social isolation on such a massive scale as we have in
response to coronavirus disease 2019 (COVID-19). However, we know that the social …

The stream of thought can flow freely, without much guidance from attention or cognitive
control. What determines what we think about from one moment to the next? Spontaneous …

Reduced executive control is a hallmark of neurocognitive aging. Poor modulation of lateral
pFC activity in the context of increasing task challenge in old adults and a “failure to …

The intrinsic functional organization of the brain changes into older adulthood. Age
differences are observed at multiple spatial scales, from global reductions in modularity and …