Fungi cause serious infections in the immunocompromised and debilitated, and the
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …

Fungal pathogens are a growing threat to public health. As human immunodeficiency
becomes increasingly common, fungal infections are becoming more prevalent. The use of …

Silver nanoparticles have been shown to be detrimental to fungal cells although the
mechanism (s) of action have not been clearly established. In this study, we used Candida …

Infections by fungal pathogens such as Candida albicans and Aspergillus fumigatus and
their resistance to triazole drugs are major concerns. Fungal lanosterol 14α-demethylase …

There are relatively few classes of antifungal drugs. This restricts clinicians' therapeutic
choices and these choices are further reduced by the emergence of drug resistance …

Resistance to antifungal drugs is an increasingly significant clinical problem. The most
common antifungal resistance encountered is efflux pump-mediated resistance of Candida …

The opportunistic human pathogens Candida albicans and other non-albicans species have
acquired considerable significance in the recent past due to the enhanced susceptibility of …

Traditional antimicrobials are increasingly suffering from the emergence of multidrug
resistance among pathogenic microorganisms. To overcome these deficiencies, a range of …

The study of eukaryotic membrane proteins has been hampered by a paucity of systems that
achieve consistent high-level functional protein expression. We report the use of a modified …

The fungal plasma membrane proton pump Pma1 is an integral plasma membrane protein
of the P-type ATPase family. It is an essential enzyme responsible for maintaining a constant …