Skin injuries across the body continue to disrupt everyday life for millions of patients and
result in prolonged hospital stays, infection, and death. Advances in wound healing devices …

Poor wound healing after diabetes mellitus remains a challenging problem, and its
pathophysiological mechanisms have not yet been fully elucidated. Persistent bleeding …

Diabetic foot ulcers and other chronic wounds with impaired healing can be treated with
bioengineered skin or with growth factors. However, most patients do not benefit from these …

Current treatment options for foot ulcers, a serious and prevalent complication of diabetes,
remain nonspecific. In this Perspective, we present recent advances in understanding the …

Diabetic foot ulceration (DFU) is a devastating complication of diabetes whose pathogenesis
remains incompletely understood. Here, we profile 174,962 single cells from the foot …

Myofibroblasts are contractile, α-smooth muscle actin-positive cells with multiple roles in
pathophysiological processes. Myofibroblasts mediate wound contractions, but their …

Wound healing is a dynamic and highly regulated process that can be separated into three
overlapping and interdependent phases: inflammation, proliferation, and remodelling. This …

The high level of reactive oxygen species (ROS) and bacterial infection impede wound
healing of the diabetic wound. Here, benefiting from the antioxidation effects of tannic acid …

Diabetic foot ulceration is a devastating diabetic complication with unmet needs. We
explored the efficacy of calcium-crosslinked alginate dressings in topically delivering …

Nonhealing diabetic foot ulcers (DFUs) are characterized by low-grade chronic
inflammation, both locally and systemically. We prospectively followed a group of patients …