Resistance to β-lactam antibiotics is rapidly growing, substantially due to the spread of
serine-β-lactamases (SBLs) and metallo-β-lactamases (MBLs), which efficiently catalyse β …

Infections caused by metallo-β-lactamase (MBL)-producing Enterobacterales and
Pseudomonas are increasingly reported worldwide and are usually associated with high …

Background In vitro data support the use of combination of aztreonam (ATM) with
ceftazidime-avibactam (CAZ-AVI), but clinical studies are lacking. The aim of our study was …

The spread of metallo-β-lactamase (MBL)-producing Enterobacterales worldwide without
the simultaneous increase in active antibiotics makes these organisms an urgent public …

Antibiotics, considered a “wonder medication” in the 20th century, have been exploited to
such an extent that bacteria have developed resistance against them giving rise to highly …

Background Bloodstream infection due to beta-lactamase and carbapenemase-producing
gram-negative bacteria poses a substantial challenge to the effectiveness of antimicrobial …

Abstract Limited data about New Delhi metallo-β-lactamase (NDM) bacteremia are
available. Blood isolates from 40 patients with NDM bacteremia were studied for antibiotic …

Background Routine microbiology results are a valuable source of antimicrobial resistance
(AMR) surveillance data in low-and middle-income countries (LMICs) as well as in high …

Introduction: Over the past few decades, antimicrobial resistance (AMR) has skyrocketed
globally among bacteria within the Family Enterobacteriaceae (ie Enterobacter spp …

Background Cefiderocol and ceftazidime-avibactam plus aztreonam (CZA-ATM) are
preferred treatment regimens for New Delhi metallo-β-lactamase (NDM)-producing …