V asculogenesis and angiogenesis are the funda-mental processes by which new blood
vessels are formed (Carmeliet, 2000; Risau, 1997; Risau and Flamme, 1995) …

Decorin, a prototype member of the growing family of the small leucine-rich proteoglycans
(SLRP's), plays significant roles in tissue development and assembly, as well as playing …

In humans, the uterus undergoes a dramatic transformation to form an endometrial stroma-
derived secretory tissue, termed decidua, during early pregnancy. The decidua secretes …

During angiogenesis, endothelial cell growth, migration, and tube formation are regulated by
pro-and anti-angiogenic factors, matrix-degrading proteases, and cell–extracellular matrix …

Regulated cell growth results from the biological balance between soluble growth‐
regulating factors, their receptors and the elicited signal cascade on the one hand side and …

Angiogenesis, the formation of new blood vessels from preexisting vessels, is a highly
complex process. It is regulated in a finely-tuned manner by numerous molecules including …

The progressive growth of most neoplasms is dependent upon the establishment of new
blood vessels, a process regulated by tumor-secreted factors and matrix proteins. We …

Decorin is a multifunctional proteoglycan that is expressed by sprouting endothelial cells. Its
expression supports capillary formation and cell survival. Previously, it was shown that some …

SPARC, a 32-kDa matricellular glycoprotein, mediates interactions between cells and their
extracellular matrix, and targeted deletion of Sparc results in compromised extracellular …

The principal extracellular matrix (ECM) chondroitin/dermatan sulfate proteoglycans include
members of two gene families—the large aggregating chondroitin sulfate proteoglycans …