Summary As coronavirus disease 2019 (COVID-19) spreads across the world, the intensive
care unit (ICU) community must prepare for the challenges associated with this pandemic …

Objectives: Screen individuals based on exposure and symptom criteria to identify potential
COVID-19 cases. Identify the clinical features and radiological findings expected in patients …

Objectives: Describe the clinical manifestations, including extrapulmonary manifestations of
COVID-19. Outline the latest treatments available in the management of COVID-19 …

Background The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the cause of a rapidly spreading illness, Coronavirus Disease 2019 (COVID-19), affecting …

Type 1 interferons have a broad antiviral activity in vitro and are currently evaluated in a
clinical trial to treat MERS-CoV. In this review, we discuss preliminary data concerning the …

To the best of our knowledge, there is no published study on the use of interferon β-1a (IFN
β-1a) in the treatment of severe COVID-19. In this randomized clinical trial, the efficacy and …

Many questions on the SARS-CoV-2 pathogenesis remain to answer. The SARS-CoV-2
genome encodes some accessory proteins that are essential for infection. Notably …

Type I interferons (IFN-I) were first discovered over 60 years ago in a classical experiment by
Isaacs and Lindenman, who showed that IFN-Is possess antiviral activity. Later, it became …

Consenso colombiano de atención, diagnóstico y manejo de la infección por SARS-COV-2/COVID-19
en establecimientos de atención de la salud. Recomendaciones basadas en consenso de …

Coronaviruses (CoVs) are a group of viruses from the family Coronaviridae that can infect
humans and animals, causing mild to severe diseases. The ongoing pandemic of severe …