Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …

Atherosclerosis, a dominant and growing cause of death and disability worldwide, involves
inflammation from its inception to the emergence of complications. Targeting inflammatory …

Nanoparticles have been extensively used as carriers for the delivery of chemicals and
biomolecular drugs, such as anticancer drugs and therapeutic proteins. Natural …

Vascular disease remains the leading cause of death and disability, the etiology of which
often involves atherosclerosis. The current treatment of atherosclerosis by pharmacotherapy …

The mechanisms underlying innate immune memory have been extensively explored in the
last decades but are in fact largely unknown. Although the specificity of adaptive immune …

Macrophages play a central role in the development of atherosclerotic cardiovascular
disease (ASCVD), which encompasses coronary artery disease, peripheral artery disease …

Cardiovascular disease, with atherosclerosis as the major underlying factor, remains the
leading cause of death worldwide. It is well established that cholesterol ester-enriched foam …

Traditionally, the innate and adaptive immune systems are differentiated by their specificity
and memory capacity. In recent years, however, this paradigm has shifted: Cells of the …

Immunotherapy is revolutionizing the treatment of diseases in which dysregulated immune
responses have an important role. However, most of the immunotherapy strategies currently …

Despite the tremendous potential of peptide-based cancer vaccines, their efficacy has been
limited in humans. Recent innovations in tumour exome sequencing have signalled the new …