[HTML][HTML] Gender and sex-related differences in normal tissue effects induced by platinum compounds
LG Marcu - Pharmaceuticals, 2022 - mdpi.com
Gender medicine in the field of oncology is an under-researched area, despite the existing
evidence towards gender-dependent response to therapy and treatment-induced adverse …
evidence towards gender-dependent response to therapy and treatment-induced adverse …
[HTML][HTML] Role of Nigella sativa and Its Constituent Thymoquinone on Chemotherapy-Induced Nephrotoxicity: Evidences from Experimental Animal Studies
M Cascella, G Palma, A Barbieri, S Bimonte… - Nutrients, 2017 - mdpi.com
Background: Most chemotherapeutic drugs are known to cause nephrotoxicity. Therefore,
new strategies have been considered to prevent chemotherapy-induced nephrotoxicity. It is …
new strategies have been considered to prevent chemotherapy-induced nephrotoxicity. It is …
[HTML][HTML] Ameliorative effects of metformin on renal histologic and biochemical alterations of gentamicin-induced renal toxicity in Wistar rats
FG Amini, M Rafieian-Kopaei… - Journal of research in …, 2012 - ncbi.nlm.nih.gov
Background: The aim of this study was to test the potential properties of metformin (MF) to
protect the kidney from gentamicin (GM)-induced renal toxicity. Materials and Methods: In …
protect the kidney from gentamicin (GM)-induced renal toxicity. Materials and Methods: In …
[HTML][HTML] Preventive and curative effects of ginger extract against histopathologic changes of gentamicin-induced tubular toxicity in rats
H Nasri, M Nematbakhsh, S Ghobadi… - … journal of preventive …, 2013 - ncbi.nlm.nih.gov
Background: Gentamicin (GM) is a commonly used aminoglycoside, however, renal toxicity
has limited its usage. This study was designed to evaluate the curative and protective effects …
has limited its usage. This study was designed to evaluate the curative and protective effects …
Unique sex-and age-dependent effects in protective pathways in acute kidney injury
R Boddu, C Fan, S Rangarajan… - American Journal …, 2017 - journals.physiology.org
Sex and age influence susceptibility to acute kidney injury (AKI), with young females
exhibiting lowest incidence. In these studies, we investigated mechanisms which may …
exhibiting lowest incidence. In these studies, we investigated mechanisms which may …
[HTML][HTML] Gender difference in Cisplatin-induced nephrotoxicity in a rat model: greater intensity of damage in male than female
M Nematbakhsh, S Ebrahimian… - Nephro-urology …, 2013 - ncbi.nlm.nih.gov
Materials and Methods Low dose of CP (1 mg/kg/day; ip) was administered daily to male
and female Wistar rats for 15 consecutive days. Serum creatinine (Cr), blood urea nitrogen …
and female Wistar rats for 15 consecutive days. Serum creatinine (Cr), blood urea nitrogen …
High-intensity interval training is more effective than continuous training to reduce inflammation markers in female rats with cisplatin nephrotoxicity
AB Leite, HN Lima, C de Oliveira Flores, CA Oliveira… - Life Sciences, 2021 - Elsevier
Aims Cisplatin (CP) is an antineoplastic widely used in the treatment of various solid tumors,
however, its clinical application is limited by nephrotoxicity. Here, we compared the impact of …
however, its clinical application is limited by nephrotoxicity. Here, we compared the impact of …
Comparison of the ameliorative roles of crab chitosan nanoparticles and mesenchymal stem cells against cisplatin-triggered nephrotoxicity
AA Shati, J Alkabli, MY Alfaifi, SEI Elbehairi… - International Journal of …, 2023 - Elsevier
Aim In the present investigation, we compared the effects of mesenchymal stem cells
extracted from bone marrow (BMSCs) and crab chitosan nanoparticles (CCNPs) on renal …
extracted from bone marrow (BMSCs) and crab chitosan nanoparticles (CCNPs) on renal …
[HTML][HTML] Time course of cisplatin-induced nephrotoxicity and hepatotoxicity
Z Pezeshki, A Khosravi, M Nekuei… - Journal of …, 2017 - ncbi.nlm.nih.gov
Background: One of the main therapeutic limitations of cisplatin (CP) is nephrotoxicity which
is time-dependent. Objectives: The purpose of this study was to determine the optimal timing …
is time-dependent. Objectives: The purpose of this study was to determine the optimal timing …
[HTML][HTML] Cisplatin-induced nephrotoxicity; protective supplements and gender differences
M Nematbakhsh, Z Pezeshki, FE Jazi… - Asian Pacific journal …, 2017 - ncbi.nlm.nih.gov
Cisplatin (CDDP) has been widely used as a chemotherapeutic agent for solid tumors. The
most common side effect of CDDP is nephrotoxicity, and many efforts have been made in the …
most common side effect of CDDP is nephrotoxicity, and many efforts have been made in the …