Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Multifunctional self-assembled peptide hydrogels for biomedical applications

M Sedighi, N Shrestha, Z Mahmoudi, Z Khademi… - Polymers, 2023 - mdpi.com
Self-assembly is a growth mechanism in nature to apply local interactions forming a
minimum energy structure. Currently, self-assembled materials are considered for …

Hierarchical nanomaterials assembled from peptoids and other sequence-defined synthetic polymers

Z Li, B Cai, W Yang, CL Chen - Chemical Reviews, 2021 - ACS Publications
In nature, the self-assembly of sequence-specific biopolymers into hierarchical structures
plays an essential role in the construction of functional biomaterials. To develop synthetic …

Perspective on the Martini model

SJ Marrink, DP Tieleman - Chemical Society Reviews, 2013 - pubs.rsc.org
The Martini model, a coarse-grained force field for biomolecular simulations, has found a
broad range of applications since its release a decade ago. Based on a building block …

Improved parameters for the martini coarse-grained protein force field

DH De Jong, G Singh, WFD Bennett… - Journal of chemical …, 2013 - ACS Publications
The Martini coarse-grained force field has been successfully used for simulating a wide
range of (bio) molecular systems. Recent progress in our ability to test the model against …

Lipid-based nanovesicles for nanomedicine

N Grimaldi, F Andrade, N Segovia… - Chemical society …, 2016 - pubs.rsc.org
Molecular self-assembly has enabled the fabrication of biologically inspired, advanced
nanostructures as lipid-based nanovesicles (L-NVs). The oldest L-NVs, liposomes, have …

Self-assembling peptide-based building blocks in medical applications

H Acar, S Srivastava, EJ Chung… - Advanced drug delivery …, 2017 - Elsevier
Peptides and peptide-conjugates, comprising natural and synthetic building blocks, are an
increasingly popular class of biomaterials. Self-assembled nanostructures based on …

Oral administration of miR-30d from feces of MS patients suppresses MS-like symptoms in mice by expanding Akkermansia muciniphila

S Liu, RM Rezende, TG Moreira, SK Tankou, LM Cox… - Cell host & …, 2019 - cell.com
Fecal transfer from healthy donors is being explored as a microbiome modality. MicroRNAs
(miRNAs) have been found to affect the microbiome. Multiple sclerosis (MS) patients have …

A close look at molecular self-assembly with the transmission electron microscope

A Rizvi, JT Mulvey, BP Carpenter, R Talosig… - Chemical …, 2021 - ACS Publications
Molecular self-assembly is pervasive in the formation of living and synthetic materials.
Knowledge gained from research into the principles of molecular self-assembly drives …

Biomedical applications of self-assembling peptides

M Rad-Malekshahi, L Lempsink, M Amidi… - Bioconjugate …, 2016 - ACS Publications
Self-assembling peptides have gained increasing attention as versatile molecules to
generate diverse supramolecular structures with tunable functionality. Because of the …