Mesenchymal stem cells for neurological disorders

A Andrzejewska, S Dabrowska, B Lukomska… - Advanced …, 2021 - Wiley Online Library
Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …

Brain repair mechanisms after cell therapy for stroke

R Rust, LR Nih, L Liberale, H Yin, M El Amki, LK Ong… - Brain, 2024 - academic.oup.com
Cell-based therapies hold great promise for brain repair after stroke. While accumulating
evidence confirms the preclinical and clinical benefits of cell therapies, the underlying …

Gut dysbiosis in stroke and its implications on Alzheimer's disease‐like cognitive dysfunction

J Cho, YJ Park, B Gonzales‐Portillo… - CNS Neuroscience …, 2021 - Wiley Online Library
Various neurological disorders, such as stroke and Alzheimer's disease (AD), involve
neuroinflammatory responses. The advent of the gut‐brain axis enhances our …

Electroacupuncture facilitates the integration of a grafted TrkC‐modified mesenchymal stem cell‐derived neural network into transected spinal cord in rats via …

Y Yang, HY Xu, QW Deng, GH Wu… - CNS neuroscience & …, 2021 - Wiley Online Library
Aims This study was aimed to investigate whether electroacupuncture (EA) would increase
the secretion of neurotrophin‐3 (NT‐3) from injured spinal cord tissue, and, if so, whether the …

The beneficial effects of chick embryo extract preconditioning on hair follicle stem cells: A promising strategy to generate Schwann cells

S Pandamooz, B Jurek, M Dianatpour… - Cell …, 2023 - Wiley Online Library
The beneficial effects of hair follicle stem cells in different animal models of nervous system
conditions have been extensively studied. While chick embryo extract (CEE) has been used …

The beneficial potential of genetically modified stem cells in the treatment of stroke: a review

MS Salehi, A Safari, S Pandamooz, B Jurek… - Stem cell reviews and …, 2022 - Springer
The last two decades have witnessed a surge in investigations proposing stem cells as a
promising strategy to treat stroke. Since growth factor release is considered as one of the …

Probing interleukin-6 in stroke pathology and neural stem cell transplantation

GM Lockard, A Alayli, M Monsour, J Gordon… - International Journal of …, 2022 - mdpi.com
Stem cell transplantation is historically understood as a powerful preclinical therapeutic
following stroke models. Current clinical strategies including clot busting/retrieval are limited …

Therapeutic potential of hair follicle-derived stem cell intranasal transplantation in a rat model of ischemic stroke

SM Mousavi, B Akbarpour, S Karimi-Haghighi… - BMC neuroscience, 2022 - Springer
Background Stem cell-based therapy has received considerable attention as a potential
candidate in the treatment of ischemic stroke; however, employing an appropriate type of …

Three-dimensional imaging in stem cell-based researches

F Nowzari, H Wang, A Khoradmehr… - Frontiers in Veterinary …, 2021 - frontiersin.org
Stem cells have an important role in regenerative therapies, developmental biology studies
and drug screening. Basic and translational research in stem cell technology needs more …

Preconditioning with secretome of neural crest-derived stem cells enhanced neurotrophic expression in mesenchymal stem cells

S Karimi-Haghighi, S Chavoshinezhad, A Safari… - Neuroscience …, 2022 - Elsevier
During the last 20 years, stem cell therapy has been considered as an effective approach for
regenerative medicine. Due to poor ability of stem cells to survive following transplantation, it …