Liquid–liquid phase separation (LLPS) is a novel principle for explaining the precise spatial
and temporal regulation in living cells. LLPS compartmentalizes proteins and nucleic acids …

The shortening of human telomeres has two opposing effects during cancer development.
On the one hand, telomere shortening can exert a tumour-suppressive effect through the …

Genome-wide association studies (GWAS) were successful to identify genetic factors
robustly associated with lung cancer. This review aims to synthesize the literature in this field …

METHODS: LTL was measured in blood samples from 490 newborns and their parents.
RESULTS: LTL (mean±SD) was longer (9.50±0.70 kb) in newborns than in their mothers …

Epidemiological studies have principally relied on measurements of telomere length (TL) in
leucocytes, which reflects TL in other somatic cells. Leucocyte TL (LTL) displays vast …

Cancer is considered the most important clinical, social and economic issue regarding
cause‑specific disability‑adjusted life years among all human pathologies. Exogenous …

Epidemiological studies have reported inconsistent associations between telomere length
(TL) and risk for various cancers. These inconsistencies are likely attributable, in part, to …

Individuals with short telomeres should be at increased risk for cancer, since short telomeres
lead to genomic instability–a hallmark of cancer. However, individuals with long telomeres …

The association between telomere length (TL) in peripheral blood cells and cancer risk
remains inconclusive. We carried out a meta-analysis on prospective studies. The study …

Background: Results regarding telomere length and cancer risk are conflicting. We tested
the hypothesis that long telomeres are associated with increased risk of any cancer and …