A systematic review on anti-diabetic plant essential oil compounds: Dietary sources, effects, molecular mechanisms, and safety

GR Gandhi, VE Hillary, PJ Antony… - Critical reviews in …, 2024 - Taylor & Francis
Type 2 diabetes mellitus (T2DM) is a multifaceted metabolic syndrome defined through the
dysfunction of pancreatic β-cells driven by a confluence of genetic and environmental …

A Review on Cistus sp.: Phytochemical and Antimicrobial Activities

I Zalegh, M Akssira, M Bourhia, F Mellouki, N Rhallabi… - Plants, 2021 - mdpi.com
Resistance to drugs is reaching alarming levels and is placing human health at risk. With the
lack of new antimicrobials drugs, infectious diseases are becoming harder to treat. Hence …

Terpenoids with special pharmacological significance: A review

R Jaeger, E Cuny - Natural product communications, 2016 - journals.sagepub.com
Terpenoids are a very prominent class of natural compounds produced in diverse genera of
plants, fungi, algae and sponges. They gained significant pharmaceutical value since …

Genus Cistus: a model for exploring labdane-type diterpenes' biosynthesis and a natural source of high value products with biological, aromatic, and pharmacological …

D Papaefthimiou, A Papanikolaou, V Falara… - Frontiers in …, 2014 - frontiersin.org
The family Cistaceae (Angiosperm, Malvales) consists of 8 genera and 180 species, with 5
genera native to the Mediterranean area (Cistus, Fumara, Halimium, Helianthemum, and …

Advances on natural abietane, labdane and clerodane diterpenes as anti-cancer agents: Sources and mechanisms of action

R Acquaviva, GA Malfa, MR Loizzo, J Xiao, S Bianchi… - Molecules, 2022 - mdpi.com
Extensive research over the past decades has identified numerous phytochemicals that
could represent an important source of anti-cancer compounds. There is an immediate need …

Preparation of drug liposomes by thin-film hydration and homogenization

B Xiang, DY Cao - Liposome-based drug delivery systems, 2021 - Springer
Among the methods for liposome preparation, thin-film hydration is one of the most
commonly used methods, which will produce heterogeneous multilamellar vesicles (MLVs) …

Preparation, characterization and anti-proliferative effects of sclareol-loaded solid lipid nanoparticles on A549 human lung epithelial cancer cells

H Hamishehkar, MB Bahadori, S Vandghanooni… - Journal of Drug Delivery …, 2018 - Elsevier
Here, sclareol-loaded solid lipid nanoparticles (sclareol-SLNs) was formulated and tested
for potential geno-cytotoxicity upon A549 lung cancer cells. Sclareol-SLNs was formulated …

Emerging role of terpenoids for the treatment of cancer: A review

B Chopra, AK Dhingra, KL Dhar… - Mini Reviews in …, 2021 - ingentaconnect.com
Aim: Terpenes are natural compounds found in several organisms belonging to the animal
and plant kingdom, therefore, constitute the largest class of natural products and were a rich …

Sclareol-loaded hyaluronan-coated PLGA nanoparticles: Physico-chemical properties and in vitro anticancer features

D Cosco, R Mare, D Paolino, MC Salvatici… - International journal of …, 2019 - Elsevier
Abstract Sclareol (labd‑14‑ene‑8, 13‑diol), a phytochemical compound belonging to labdane-
type diterpenes, has recently attracted noteworthy attention because of its peculiar …

A Copal-8-ol Diphosphate Synthase from the Angiosperm Cistus creticus subsp. creticus Is a Putative Key Enzyme for the Formation of Pharmacologically Active …

V Falara, E Pichersky, AK Kanellis - Plant physiology, 2010 - academic.oup.com
The resin of Cistus creticus subsp. creticus, a plant native to Crete, is rich in labdane-type
diterpenes with significant antimicrobial and cytotoxic activities. The full-length cDNA of a …