Pathogenicity and virulence of Hepatitis B virus
Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …
an estimated 296 million people in the world that are chronically infected by this virus, and …
Protein neddylation and its role in health and diseases
NEDD8 (Neural precursor cell expressed developmentally downregulated protein 8) is an
ubiquitin-like protein that is covalently attached to a lysine residue of a protein substrate …
ubiquitin-like protein that is covalently attached to a lysine residue of a protein substrate …
原发性肝癌流行现状, 主要发病机制及防控策略
鲜林峰， 方乐天， 刘文斌， 赵沛， 陈一凡， 曹广文 - 中国癌症防治杂志, 2022 - zgazfz.com
原发性肝癌是世界范围内主要的癌症死亡原因之一, 早期筛查高危人群并进行有效的三级预防是
当前降低肝癌死亡率的主要策略. 本文总结了目前原发性肝癌的流行特征和主要致病因素; …
当前降低肝癌死亡率的主要策略. 本文总结了目前原发性肝癌的流行特征和主要致病因素; …
Transcription factor E4F1 as a regulator of cell life and disease progression
S Sun, B Zhong, X Zeng, J Li, Q Chen - Science Advances, 2023 - science.org
E4F transcription factor 1 (E4F1), a member of the GLI-Kruppel family of zinc finger proteins,
is now widely recognized as a transcription factor. It plays a critical role in regulating various …
is now widely recognized as a transcription factor. It plays a critical role in regulating various …
[HTML][HTML] Protein arginine methylation in viral infection and antiviral immunity
K Zheng, S Chen, Z Ren, Y Wang - International journal of …, 2023 - ncbi.nlm.nih.gov
Protein arginine methyltransferase (PRMT)-mediated arginine methylation is an important
post-transcriptional modification that regulates various cellular processes including …
post-transcriptional modification that regulates various cellular processes including …
[PDF][PDF] 乙型肝炎病毒X 基因及其变异促肝细胞癌的作用机制
周鑫宇， 柳东红， 蔡仕良， 陈宏森， 何奕达， 王瑞华… - 中国癌症防治 …, 2022 - zgazfz.com
原发性肝癌居我国非成熟死亡原因的首位, 其中肝细胞癌(hepatocellular carcinoma, HCC)
占90% 以上. 慢性乙型肝炎病毒(hepatitis B virus, HBV) 感染是HCC 发生的主要原因. HBV …
占90% 以上. 慢性乙型肝炎病毒(hepatitis B virus, HBV) 感染是HCC 发生的主要原因. HBV …
Heat shock protein family A member 8 serving as a co-activator of transcriptional factor ETV4 up-regulates PHLDA2 to promote the growth of liver cancer
S Wang, Y Wang, G Yang, H Zhang, H Yuan… - Acta Pharmacologica …, 2023 - nature.com
Heat shock protein family A member 8 (HSPA8) participates in the folding or degradation of
misfolded proteins under stress and plays critical roles in cancer. In this study, we …
misfolded proteins under stress and plays critical roles in cancer. In this study, we …
TRIM26 inhibits hepatitis B virus replication by promoting HBx degradation and TRIM26 genetic polymorphism predicts PegIFNα treatment response of HBeAg …
M Luo, J Hou, H Mai, J Chen, H Chen… - Alimentary …, 2022 - Wiley Online Library
Summary Background Hepatitis B virus (HBV) infection is a serious global health burden.
TRIM26 has been reported to affect hepatitis C virus replication. Aims To manifest the role of …
TRIM26 has been reported to affect hepatitis C virus replication. Aims To manifest the role of …
Hepatitis B x (HBx) as a component of a functional cure for chronic hepatitis B
MA Feitelson, A Arzumanyan, I Spector, A Medhat - Biomedicines, 2022 - mdpi.com
Patients who are carriers of the hepatitis B virus (HBV) are at high risk of chronic liver
disease (CLD) which proceeds from hepatitis, to fibrosis, cirrhosis and to hepatocellular …
disease (CLD) which proceeds from hepatitis, to fibrosis, cirrhosis and to hepatocellular …
Ubiquitin: a double-edged sword in hepatitis B virus-induced hepatocellular carcinoma
A Kar, S Mukherjee, S Mukherjee, A Biswas - Virology, 2024 - Elsevier
Hepatitis B virus is one of the leading causes behind the neoplastic transformation of liver
tissue and associated mortality. Despite the availability of many therapies and vaccines, the …
tissue and associated mortality. Despite the availability of many therapies and vaccines, the …