Epilepsy, a neurological disease characterized by recurrent seizures, is highly
heterogeneous in nature. Based on the prevalence, epilepsy is classified into two types …

A central theme in the quest to unravel the genetic basis of epilepsy has been the effort to
elucidate the roles played by inherited defects in ion channels. The ubiquitous expression of …

In this report, the International League Against Epilepsy (ILAE) Genetics Commission
discusses essential issues to be considered with regard to clinical genetic testing in the …

Double bromodomain‐containing gene Brd2 is essential for embryonic development in mouse -
Shang - 2009 - Developmental Dynamics - Wiley Online Library Skip to Article Content Skip to …

Summary Background The Epilepsy Genetics (EPIGEN) Consortium was established to
undertake genetic mapping analyses with augmented statistical power to detect variants that …

The contribution of genetics to both rare and common epilepsies is rapidly being elucidated,
and neurologists are routinely considering genetic testing in the work-up of several epilepsy …

Idiopathic generalized epilepsy (IGE) syndromes represent about 30% of all epilepsies.
They have strong, but elusive, genetic components and sex-specific seizure expression …

Epigenetic pharmacotherapy for CNS-related diseases is a burgeoning area of research. In
particular, members of the bromodomain and extra-terminal domain (BET) family of proteins …

Post-traumatic seizures (PTS) are a significant complication from traumatic brain injury (TBI).
Adenosine, a major neuroprotective and neuroinhibitory molecule, is important in …

Epilepsy is a network disorder driven by fundamental changes in the function of the cells
which compose these networks. Driving this aberrant cellular function are large scale …