Excess alcohol consumption with consequent alcoholic liver disease (ALD) and metabolic
syndrome-related nonalcoholic fatty liver disease (NAFLD) are recognized as the most …

Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of
lipids. Inactivation of ANGPTL3, a gene located in an intron of DOCK7, results in very low …

Objectives: Several reports indicate that the body fat compartments, especially ip fat, predict
metabolic risk better than total body fat. The objective of the study was to determine whether …

OBJECTIVE—Using the genome-wide association approach, we recently identified the
glucokinase regulatory protein gene (GCKR, rs780094) region as a novel quantitative trait …

Background The consistent finding of higher prevalence of hypertension in US blacks
compared to whites has led to speculation that African-origin populations are particularly …

OBJECTIVE To evaluate racial/ethnic differences in pancreatic triglyceride (TG) levels and
their relationship to β-cell dysfunction in humans. RESEARCH DESIGN AND METHODS We …

Background: High-density lipoprotein (HDL) cholesterol concentration (HDL-C) is an
established atheroprotective marker, in particular for coronary artery disease; however, HDL …

Results Mean age was 43±10 years, 56% of participants were women, and 52% were
African American. BP was higher in African Americans than in non–African Americans …

Objective Polycystic ovary syndrome (PCOS) is a condition of androgen excess and chronic
anovulation frequently associated with insulin resistance. We combined a nontargeted and …

An unknown fraction of the genome participates in the metabolism of sterols and vitamin D,
two classes of lipids with diverse physiological and pathophysiological roles. Here, we used …