Potential role of neuroactive tryptophan metabolites in central fatigue: establishment of the fatigue circuit

M Yamashita - International Journal of Tryptophan Research, 2020 - journals.sagepub.com
Central fatigue leads to reduced ability to perform mental tasks, disrupted social life, and
impaired brain functions from childhood to old age. Regarding the neurochemical …

Classical maple syrup urine disease and brain development: principles of management and formula design

KA Strauss, B Wardley, D Robinson… - Molecular genetics and …, 2010 - Elsevier
Branched-chain ketoacid dehydrogenase deficiency results in complex and volatile
metabolic derangements that threaten brain development. Treatment for classical maple …

Early protein malnutrition disrupts cerebellar development and impairs motor coordination

SC Ranade, MS Nawaz, PK Rambtla… - British journal of …, 2012 - cambridge.org
Maternal malnutrition affects every aspect of fetal development. The present study asked the
question whether a low-protein diet of the mother could result in motor deficits in the …

Identification and characterization of novel variants of the tryptophan 2, 3-dioxygenase gene: differential regulation in the mouse nervous system during development

M Kanai, T Nakamura, H Funakoshi - Neuroscience research, 2009 - Elsevier
Tryptophan 2, 3-dioxygenase (TDO), an initial and rate-limiting enzyme for the kynurenine
pathway of tryptophan (Trp) metabolism, is thought to play an important role in systemic Trp …

[HTML][HTML] Serotonin promotes Go-dependent neuronal migration in Caenorhabditis elegans

KS Kindt, T Tam, S Whiteman, WR Schafer - Current biology, 2002 - cell.com
Background: The directed migration of neurons during development requires attractive and
repulsive cues that control the direction of migration as well as permissive cues that …

Impact of long-rope jumping on monoamine and attention in young adults

M Yamashita, T Yamamoto - Brain sciences, 2021 - mdpi.com
Previous research has shown that rope jumping improves physical health; however, little is
known about its impact on brain-derived monoamine neurotransmitters associated with …

Effects of intra-uterine and early extra-uterine malnutrition on seizure threshold and hippocampal morphometry of pup rats

ML Florian, ML Nunes - Nutritional Neuroscience, 2011 - Taylor & Francis
We evaluate the influence of different malnutrition paradigms (intra-uterine x extra-uterine) in
body and brain weight, in seizure threshold and in hippocampus morphometry, in …

Effects of maternal L-tryptophan depletion and corticosterone administration on neurobehavioral adjustments in mouse dams and their adolescent and adult …

F Zoratto, A Berry, F Anzidei, M Fiore, E Alleva… - Progress in Neuro …, 2011 - Elsevier
Major depressive disorder (MDD), a pathology characterized by mood and neurovegetative
disturbances, depends on a multi-factorial contribution of individual predisposition (eg …

Myelin basic protein accumulation is impaired in a model of protein deficiency during development

EA Montanha-Rojas, AA Ferreira, F Tenorio… - Nutritional …, 2005 - Taylor & Francis
During the development of the central nervous system (CNS) there is a great possibility of
permanent effects in consequence of environmental disturbances. Nutritional deficiency is …

Neonatal tryptophan dietary restriction alters development of retinotectal projections in rats

ÉMC González, LA Penedo, P Oliveira-Silva… - Experimental …, 2008 - Elsevier
The specification of sensory neural circuits includes the elimination of transitory axon
collaterals/synapses that takes place during early post natal life, an important step for the …