Large injuries to bones are still one of the most challenging musculoskeletal problems.
Tissue engineering can combine stem cells, scaffold biomaterials, and biofactors to aid in …

Glioblastoma (GB) is the most aggressive type of brain tumor with heterogeneity, strong
invasive ability, and high resistance to therapy due to immunosuppressive mechanisms …

CD73 (ecto-5′-nucleotidase) has emerged as an attractive target for cancer
immunotherapy of many cancers. CD73 catalyzes the hydrolysis of adenosine …

The purinergic system is fundamental in the tumor microenvironment, since it regulates
tumor cell interactions with the immune system, as well as growth and differentiation in …

Cancer is one of the leading causes of mortality worldwide. As the population increases,
there is an enriched thrust for screening a newer delivery system for anticancer agents to …

Glioblastoma multiforme (GBM) is a complicated and heterogeneous brain tumor with short-
term survival outcomes. Commercial therapies are not practical due to cell infiltration …

Background: Neuronal cell ferroptosis following intracerebral hemorrhage (ICH) is a crucial
factor contributing to the poor prognosis of ICH patients. The objective of this investigation …

Adenosine triphosphate (ATP) and its metabolites adenosine diphosphate, adenosine
monophosphate, and adenosine in purinergic signaling pathway play important roles in …

Background Despite the development of various therapeutic approaches over the past
decades, the treatment of glioblastoma multiforme (GBM) remains a major challenge. The …

CD73 molecule inhibitor upregulates miR16 expression in experimental glioblastoma and
inhibits angiogenesis by targeting VEGF Page 1 Page 1/21 CD73 molecule inhibitor upregulates …