Natural compounds have significant anticancer pharmacological activities, but often suffer
from low bioavailability and selectivity that limit therapeutic use. The present work critically …

Conventional chemotherapeutics exploration is hampered due to their nonspecific
distribution leading to unintended serious toxicity. Toxicity is so severe that deciding to go for …

Despite the clinical approval of few nanomedicines for cancer therapy, some drawbacks still
impede their improved efficiency including low drug loading, off-target toxicity and …

The birth of RNAi technology has pioneered actionability at the molecular level. Compared
to DNA, RNA is less stable and therefore requires more demanding delivery vehicles. With …

Despite considerable advances in cancer treatment, chemotherapy remains a cornerstone
in breast cancer therapy. Therefore, reducing chemoresistance and adverse effects of …

Introduction: The use of herbal compounds in cancer therapy has great potential to promote
the efficacy of current cancer therapeutic strategies. Herbal compounds were successfully …

Human serum albumin or simply called albumin is a flexible protein employed as a carrier in
the fabrication of albumin-based nanocarriers (ANCs) for the administration of cancer …

The current treatment protocols for breast cancer have shifted from single agent therapies to
combinatorial approaches that offer synergistic efficacies and reduced side effects. Self …

Abstract α-Mangostin, a xanthone derivative from the pericarp of Garcinia mangostana L.,
has numerous bioactivities and pharmacological properties. However, α-mangostin has low …

Background The long-term sequelae and serious side effects of conventional breast cancer
chemotherapy due to ubiquitous biodistribution and systemic toxicity remain the main …