OBJECTIVE High-grade gliomas (HGGs) continue to carry poor prognoses, and patient
outcomes depend heavily on the extent of resection (EOR). The utility of conventional image …

Safely maximizing extent of resection has become the central goal in glioma surgery.
Especially in eloquent cortex, the goal of maximal resection is balanced with neurological …

Abstract Introduction 5-aminolevulinic acid (5-ALA) was approved by the FDA in June 2017
as an intra-operative optical imaging agent for patients with gliomas (suspected World …

Purpose: In glioma surgery, it is critical to maximize tumor resection without compromising
adjacent noncancerous brain tissue. Optical coherence tomography (OCT) is a noninvasive …

Maximal safe resection represents the gold standard for surgery of malignant brain tumors.
As regards gross-total resection, accurate localization and precise delineation of the tumor …

Purpose Fluorescence guided surgery by 5-aminolevulinic acid (5-ALA) and intraoperative
MRI (iMRI) are currently the most important intraoperative imaging techniques in high grade …

Malignant glioma surgery involves the challenge of preserving the neurological status of
patients harboring these lesions while pursuing a maximal tumor resection, which is …

Simple Summary In the era of targeted therapies, achieving a maximal safe resection still
remains a critical prognosis factor in diffuse low-grade gliomas and represents the goal to …

Background When feasible, the surgical resection is the standard first step of the
management of high-grade gliomas. 5-ALA fluorescence-guided-surgery (5-ALA-FGS) was …

OBJECTIVE Intraoperative ultrasonography (IOUS) is a widely accessible imaging modality
that provides real-time surgical guidance with minimal identified risk or additional operative …