A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

The effects of cell therapy on heart regeneration in patients with chronic cardiomyopathy
have been assessed in several clinical trials. These trials can be categorized as those using …

Despite significant therapeutic advances, the prognosis of patients with heart failure (HF)
remains poor, and current therapeutic approaches are palliative in the sense that they do not …

Introduction 'Patient-specific'induced pluripotent stem cells (iPSCs) are attractive because
they can generate abundant cells without the risk of immune rejection for cell therapy …

Rationale: Although accumulating data support the efficacy of intramyocardial cell-based
therapy to improve left ventricular (LV) function in patients with chronic ischemic …

Heart failure is the leading cause of death worldwide, and current therapies only delay
progression of the disease. Laboratory experiments and recent clinical trials suggest that …

Background—Despite rapid clinical translation and widespread enthusiasm, the therapeutic
benefits of adult bone marrow cell (BMC) transplantation in patients with ischemic heart …

Endothelial progenitor cells (EPCs) have been isolated and shown to be effective in animal
models of ischemia, and many groups involved in clinical trials have demonstrated that EPC …

Background A promising approach to the treatment of chronic ischaemic heart disease and
congestive heart failure is the use of stem cells. The last decade has seen a plethora of …

Therapeutic angiogenesis may improve outcomes in patients with coronary artery disease
undergoing surgical revascularization. Angiogenic factors may promote blood vessel growth …