N Hussain, A Ahmed… - Asian Journal of Organic …, 2020 - Wiley Online Library
Glycals are unsaturated sugars having an enolic double bond present inside the ring and act as a versatile synthon for the synthesis of natural products and biologically important …
É Juhász-Tóth, ÁS Malecz, M Tóth, Á Homolya… - New Journal of …, 2023 - pubs.rsc.org
A series of 2-iodo-1-C-substituted glycals having electron withdrawing groups (CN, CO2CH3, CONH2) at the C-1 carbon were synthesized from the parent 1-C-substituted …
Pd-catalyzed carbonylative cross-coupling reactions of 2-iodoglycals have been developed for the synthesis of sugar-based arylones and ynones using formic acid as the carbonyl …
RV Veloso, A Shamim, Y Lamarrey, HA Stefani… - Bioorganic …, 2021 - Elsevier
The sickle cell disease (SCD) has a genetic cause, characterized by a replacement of glutamic acid to valine in the β-chain of hemoglobin. The disease has no effective treatment …
MP Darbem, KS Kanno, IM de Oliveira… - New Journal of …, 2019 - pubs.rsc.org
The synthesis of amidoglucals and glucal esters in good to high yields using 2-iodo-3, 4, 6- tri-O-acetyl-D-glucal as a substrate, Mo (CO) 6 as a carbon monoxide source and PdCl2 as …
M Malinowski, T Van Tran… - Advanced Synthesis …, 2020 - Wiley Online Library
Access to unprotected 2‐cyano‐glycals via a mild palladium‐catalyzed cyanation of protecting groups‐free 2‐iodoglycals in aqueous media has been developed. Diverse glycal …
A carbonylative Sonogashira coupling approach to the synthesis of glyco-alkynones is described. Eighteen examples were obtained in moderate do nearly quantitative yields …
A Shamim, FB Souza, SNS Vasconcelos, HA Stefani - Tetrahedron letters, 2017 - Elsevier
A library of glucal-derived triazoles have been synthesized using the copper-catalyzed azide- alkyne cyclization reaction starting from 3, 4, 6-tri-O-acetyl-d-glucal. Different trimethylsilyl …
2, 3-Unsaturated C-(triazolyl) glycosyl acetates have been synthesized from 3, 4, 6-tri-O- acetyl-d-glucal using C-glycosylation and click chemistry and were then used in a palladium …