Cadherins are transmembrane proteins that mediate cell–cell adhesion in animals. By
regulating contact formation and stability, cadherins play a crucial role in tissue …

This review addresses the cellular and molecular mechanisms of cadherin-based tissue
morphogenesis. Tissue physiology is profoundly influenced by the distinctive organizations …

Classical cadherin cell-cell adhesion proteins play key morphogenetic roles during
development and are essential for maintaining tissue integrity in multicellular organisms …

Biological processes rely on molecular interactions that can be directly measured using
force spectroscopy techniques. Here we review how atomic force microscopy can be applied …

As the ability to analyze individual cells in microbial populations expands, it is becoming
apparent that isogenic microbial populations contain substantial cell-to-cell differences in …

Cell adhesions link cells to the extracellular matrix (ECM) and to each other and depend on
interactions with the actin cytoskeleton. Both cell–ECM and cell–cell adhesion sites contain …

Cells integrate biochemical and mechanical information to function within multicellular
tissue. Within developing and remodeling tissues, mechanical forces contain instructive …

The establishment and maintenance of precisely organized tissues requires the formation of
sharp borders between distinct cell populations. The maintenance of segregated cell …

Classical cadherin Ca2+-dependent cell–cell adhesion proteins play key roles in
embryogenesis and in maintaining tissue integrity. Cadherins mediate robust adhesion by …

With the recent revolution in Molecular Biology and the deciphering of the Human Genome,
understanding of the building blocks that comprise living systems has advanced rapidly. We …