Research on astronaut health and model organisms have revealed six features of
spaceflight biology that guide our current understanding of fundamental molecular changes …

Motivation To curate and organize expensive spaceflight experiments conducted aboard
space stations and maximize the scientific return of investment, while democratizing access …

Simple Summary We comparatively discuss all possible methodologies for the complex
DNA damage in situ detection. Fluorescent microscopy (FM) is the universal approach …

We present a comprehensive comparative analysis on the repair of radiation-induced DNA
damage ex vivo in 15 strains of mice, including 5 inbred reference strains and 10 …

Estimating cancer risk from space radiation has been an ongoing challenge for decades
primarily because most of the reported epidemiological data on radiation-induced risks are …

Due to high metabolic activity, proliferating cells continuously generate free radicals, which
induce DNA double-strand breaks (DSB). Fluorescently tagged nuclear foci of DNA repair …

Abstract Space travel presents unique environmental challenges that enact molecular,
cellular, and physiological changes across many regions within the human body …

Cancer is one of the most lethal and hard to cure diseases. The common treatments for
cancer include surgery, radiation therapy, chemotherapy, immunotherapy and hormone …