An overview of nanostructured lipid carriers and its application in drug delivery through different routes

S Khan, A Sharma, V Jain - Advanced pharmaceutical bulletin, 2022 - pmc.ncbi.nlm.nih.gov
Nanostructured Lipid Carriers (NLC) are nano-sized colloidal drug delivery system that
contains a lipid mixture consisting of both solid and liquid lipids in their core. This Lipid …

[HTML][HTML] Nanostructured lipid carriers and their potential applications for versatile drug delivery via oral administration

VN Thuy, TV Van, AH Dao, BJ Lee - OpenNano, 2022 - Elsevier
Enteral administration is the most convenient route despite the gastrointestinal physiological
barriers. Nanostructured lipid carriers (NLCs) have emerged as a promising strategy for …

Lipid-based oral formulation in capsules to improve the delivery of poorly water-soluble drugs

P Mohite, S Singh, A Pawar, A Sangale… - Frontiers in Drug …, 2023 - frontiersin.org
Poorly water-soluble drugs demonstrate significant challenge in pharmaceutical
development, which is linked to their limited oral bioavailability and therapeutic efficacy. To …

Codelivery of ivermectin and methyl dihydrojasmonate in nanostructured lipid carrier for synergistic antileukemia therapy

FS Abou-Elnour, SE El-Habashy, MM Essawy… - International Journal of …, 2024 - Elsevier
Chronic myeloid leukemia is a life-threatening blood-cancer prevalent among children and
adolescents. Research for innovative therapeutics combine drug-repurposing …

Enhancement of in-vitro anti-oral cancer activities of silymarin using dispersion of nanostructured lipid carrier in mucoadhesive in-situ gel

MB Shete, AS Deshpande, P Shende - International Journal of …, 2023 - Elsevier
Silymarin (SME) shows multiple therapeutic actions against several cancers, however, low
aqueous solubility and poor bioavailability issues restrict its clinical use. In this study, SME …

Lipid-based nano-sized cargos as a promising strategy in bone complications: a review

SS Hallan, J Amirian, A Brangule, D Bandere - Nanomaterials, 2022 - mdpi.com
Bone metastasis has been considered the fatal phase of cancers, which remains incurable
and to be a challenge due to the non-availability of the ideal treatment strategy. Unlike bone …

In vitro and in vivo characterization of Entacapone-loaded nanostructured lipid carriers developed by quality-by-design approach

Y Agrawal, K Patil, H Mahajan, M Potdar, P Joshi… - Drug Delivery, 2022 - Taylor & Francis
Entacapone, a reversible catechol-o-methyl transferase inhibitor, is used to enhance the
action of dopamine agonists by reducing their metabolism and the 'Wearing-off'effects …

New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in …

SA Fouad, TA Badr, A Abdelbary, M Fadel… - AAPS …, 2024 - Springer
Cellulite (CLT) is one of the commonly known lipodystrophy syndromes affecting post-
adolescent women worldwide. It is topographically characterized by an orange-peel …

A novel Posaconazole oral formulation using spray dried solid dispersion technology: in-vitro and in-vivo study

K Patel, V Kevlani, S Shah - Drug Delivery and Translational Research, 2024 - Springer
SD (solid dispersion) technology is one of the well-recognized solubility enhancement
methods; but the use of versatile carriers in ASD (amorphous SD) to achieve the added …

Development and In-Vitro Evaluation of Eugenol-Based Nanostructured Lipid Carriers for Effectual Topical Treatment Against C. albicans

SN Chilamakuri, A Kumar, AG Nath, A Gupta… - Journal of …, 2024 - Elsevier
The main objective of the experiment is to develop and evaluate hydrogel-bearing
nanostructured lipid carriers (NLCs) loaded with ketoconazole (KTZ) for the effective …