Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology

MCK Leung, PL Williams, A Benedetto… - Toxicological …, 2008 - academic.oup.com
The nematode Caenorhabditis elegans has emerged as an important animal model in
various fields including neurobiology, developmental biology, and genetics. Characteristics …

Anti-biofilm compounds derived from marine sponges

SD Stowe, JJ Richards, AT Tucker, R Thompson… - Marine drugs, 2011 - mdpi.com
Bacterial biofilms are surface-attached communities of microorganisms that are protected by
an extracellular matrix of biomolecules. In the biofilm state, bacteria are significantly more …

Application of growth-related sublethal endpoints in ecotoxicological assessments using a harpacticoid copepod

U Dahl, E Gorokhova, M Breitholtz - Aquatic toxicology, 2006 - Elsevier
In ecotoxicology, there is an increasing demand for sensitive sublethal endpoints. The
primary aim of the present study was therefore to evaluate the relative sensitivity and …

Are pharmaceuticals with evolutionary conserved molecular drug targets more potent to cause toxic effects in non-target organisms?

S Furuhagen, A Fuchs, E Lundström Belleza… - PloS one, 2014 - journals.plos.org
The ubiquitous use of pharmaceuticals has resulted in a continuous discharge into
wastewater and pharmaceuticals and their metabolites are found in the environment. Due to …

The phenotypic and behavioral defects can be transferred from zinc-exposed nematodes to their progeny

D Wang, L Shen, Y Wang - Environmental Toxicology and Pharmacology, 2007 - Elsevier
In despite of the essential functions of zinc as trace element for humans, toxic effects will be
pronounced while organisms are exposed to high levels of zinc. However, whether the …

Linking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans

S Swain, JF Wren, SR Stürzenbaum, P Kille… - BMC Systems …, 2010 - Springer
Background Physiologically based modelling using DEBtox (dynamic energy budget in
toxicology) and transcriptional profiling were used in Caenorhabditis elegans to identify how …

Insights into zinc and cadmium biology in the nematode Caenorhabditis elegans

N Dietrich, CH Tan, C Cubillas, BJ Earley… - Archives of biochemistry …, 2016 - Elsevier
Zinc is an essential metal that is involved in a wide range of biological processes, and
aberrant zinc homeostasis is implicated in multiple human diseases. Cadmium is chemically …

Evidence of population genetic effects of long-term exposure to contaminated sediments—a multi-endpoint study with copepods

J Gardeström, U Dahl, O Kotsalainen, A Maxson… - Aquatic Toxicology, 2008 - Elsevier
In the environment, pollution generally acts over long time scales and exerts exposure of
multiple toxicants on the organisms living there. Recent findings show that pollution can alter …

Settling cyanobacterial blooms do not improve growth conditions for soft bottom meiofauna

FJA Nascimento, AML Karlson, J Näslund… - Journal of Experimental …, 2009 - Elsevier
Summer blooms of the toxin-producing cyanobacteria Nodularia spumigena are frequent in
the Baltic Sea and recent findings suggest that they may be an important food source for the …

Triphenyltin exposure alters the antioxidant system, energy metabolism and the expression of genes related to physiological stress in zebrafish (Danio rerio)

P Li, ZH Li, L Zhong - Comparative Biochemistry and Physiology Part C …, 2019 - Elsevier
The adverse influences of triphenyltin (TPT) on aquatic system have been of great concern
due to their widespread use and ubiquity in water environment. Here, zebrafish larvae (7 …