First degree female relatives (FDFRs) of breast cancer patients have been reported to have
a 2-to 3-fold increase in breast cancer risk as compared with the general population …

The purpose of this study was to evaluate the role of polymorphisms in DNA repair genes as
genetic indicators of susceptibility to familial and sporadic breast cancer. We analysed DNA …

Altered DNA repair capacity can result in increased susceptibility to cancer. The base
excision repair (BER) pathway effectively removes DNA damage caused by ionizing …

Purpose We comprehensively evaluated genetic variants in DNA repair genes with
premenopausal breast cancer risk. Methods In this nested case–control study of 239 …

Background Previous studies have found a link between a low DNA repair capacity (DRC)
level and increased cancer risk. Our aim was to assess the statistical association of DRC …

The twentieth century may be looked back upon as the century of lung cancer. At the
beginning of the century lung cancer was quite rare, but this century the rates have …

With the vast technological and informational resources increasingly available from
investments in “genomics,” toxicology and much of biological science, is faced with …

Systemic oxidative stress is thought to contribute to risk of various cancers, including breast
cancer. DNA repair ability also has been associated with breast cancer risk. In this work, we …

Previous studies have found a link between a low DNA repair capacity (DRC) level and
increased risk for breast cancer (BC). A recent study by Matta et al. 2012 showed that …

The genes involved in DNA repair system play a crucial role in the protection against
mutations. It has been hypothesized that functional deficiencies in highly conserved DNA …