Classical and noncanonical functions of miRNAs in cancers
Alterations in microRNAs (miRNAs) expression are causative in the initiation and
progression of human cancers. The molecular events responsible for the widespread …
progression of human cancers. The molecular events responsible for the widespread …
Trends in the development of miRNA bioinformatics tools
L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …
recognition of cognate sequences and interference of transcriptional, translational or …
exoRBase 2.0: an atlas of mRNA, lncRNA and circRNA in extracellular vesicles from human biofluids
Extracellular vesicles (EVs) are small membranous vesicles that contain an abundant cargo
of different RNA species with specialized functions and clinical implications. Here, we …
of different RNA species with specialized functions and clinical implications. Here, we …
The bioinformatics toolbox for circRNA discovery and analysis
Circular RNAs (circRNAs) are a unique class of RNA molecule identified more than 40 years
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
Saliva diagnostics
T Nonaka, DTW Wong - Annual Review of Analytical Chemistry, 2022 - annualreviews.org
Cancer remains one of the leading causes of death, and early detection of this disease is
crucial for increasing survival rates. Although cancer can be diagnosed following tissue …
crucial for increasing survival rates. Although cancer can be diagnosed following tissue …
miEAA 2.0: integrating multi-species microRNA enrichment analysis and workflow management systems
F Kern, T Fehlmann, J Solomon, L Schwed… - Nucleic acids …, 2020 - academic.oup.com
Gene set enrichment analysis has become one of the most frequently used applications in
molecular biology research. Originally developed for gene sets, the same statistical …
molecular biology research. Originally developed for gene sets, the same statistical …
Circulating miRNA analysis for cancer diagnostics and therapy
Successful treatment of cancer depends on early diagnosis and effective monitoring of
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …
Circular RNAs: expression, localization, and therapeutic potentials
Circular RNAs (circRNAs) are RNAs with a unique circular structure that is generated from
back-splicing processes. These circular molecules were discovered more than 40 years ago …
back-splicing processes. These circular molecules were discovered more than 40 years ago …
Lnc2Cancer v2. 0: updated database of experimentally supported long non-coding RNAs in human cancers
Y Gao, P Wang, Y Wang, X Ma, H Zhi… - Nucleic acids …, 2019 - academic.oup.com
Abstract Lnc2Cancer 2.0 (http://www. bio-bigdata. net/lnc2cancer) is an updated database
that provides comprehensive experimentally supported associations between lncRNAs and …
that provides comprehensive experimentally supported associations between lncRNAs and …
Tumor-derived systems as novel biomedical tools—turning the enemy into an ally
Cancer is a complex illness that presents significant challenges in its understanding and
treatment. The classic definition," a group of diseases characterized by the uncontrolled …
treatment. The classic definition," a group of diseases characterized by the uncontrolled …