Uremic toxins in the progression of chronic kidney disease and cardiovascular disease: mechanisms and therapeutic targets

YJ Lim, NA Sidor, NC Tonial, A Che, BL Urquhart - Toxins, 2021 - mdpi.com
Chronic kidney disease (CKD) is a progressive loss of renal function. The gradual decline in
kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting …

Cardiorenal syndrome: the emerging role of protein-bound uremic toxins

S Lekawanvijit, AR Kompa, BH Wang, DJ Kelly… - Circulation …, 2012 - Am Heart Assoc
Cardiorenal syndrome is a condition in which a complex interrelationship between cardiac
dysfunction and renal dysfunction exists. Despite advances in treatment of both …

Neutrophil-to-lymphocyte ratio in relation to the risk of all-cause mortality and cardiovascular events in patients with chronic kidney disease: a systematic review and …

WM Zhao, SM Tao, GL Liu - Renal failure, 2020 - Taylor & Francis
Aim To systematically evaluate the relationship between the neutrophil-to-lymphocyte ratio
(NLR) and the risk of all-cause mortality or cardiovascular events in patients with chronic …

IL 6 but not TNF is linked to coronary artery calcification in patients with chronic kidney disease

J Kamińska, M Stopiński, K Mucha, A Jędrzejczak… - Cytokine, 2019 - Elsevier
Introduction Patients with chronic kidney disease (CKD) have a high risk of death mainly due
to cardiovascular diseases (CVD). Early risk identification may allow interventions and …

Associations between cardiovascular disease risk factors and IL-6 and hsCRP levels in the elderly

P Nadrowski, J Chudek, M Skrzypek… - Experimental …, 2016 - Elsevier
Background Age-related diseases, including cardiovascular diseases (CVD) may be
stimulated by microinflammation, marked by increased level of IL-6 and high-sensitivity CRP …

Soluble tumor necrosis factor receptor 1 and 2 predict outcomes in advanced chronic kidney disease: a prospective cohort study

N Neirynck, G Glorieux, E Schepers, F Verbeke… - PloS one, 2015 - journals.plos.org
Background Soluble tumor necrosis factor receptors 1 (sTNFR1) and 2 (sTNFR2) have been
associated to progression of renal failure, end stage renal disease and mortality in early …

Biomarkers and predictors of adverse cardiovascular events in different stages of chronic kidney disease

B Stopic, B Medic-Brkic, K Savic-Vujovic… - Dose …, 2022 - journals.sagepub.com
Chronic kidney disease (CKD) is an important factor that contributes to the increase of all-
cause morbidity and mortality in the group of non-communicable diseases, and it is also …

Dialysis modality and nutritional status are associated with variability of inflammatory markers

S Snaedal, AR Qureshi, SH Lund… - Nephrology Dialysis …, 2016 - academic.oup.com
Background Inflammation is a common feature in dialysis patients and is associated with
cardiovascular complications and poor outcome. Measuring the variability of inflammatory …

Dynamic assessment of interleukin‐6 during hemodialysis and mortality in coronavirus disease‐19

B Quiroga, P Muñoz Ramos, M Giorgi… - Therapeutic …, 2021 - Wiley Online Library
The impact of the newly discovered severe acute respiratory syndrome coronavirus 2
causing coronavirus disease‐19 (COVID‐19) in hemodialysis patients remains poorly …

Association of Red Blood Cell Distribution Width and Neutrophil-to-Lymphocyte Ratio with Calcification and Cardiovascular Markers in Chronic Kidney Disease

S Roumeliotis, IE Neofytou, C Maassen, P Lux… - Metabolites, 2023 - mdpi.com
We aimed to investigate the association between Red Blood Cell Distribution Width (RDW)
and Neutrophil-to-Lymphocyte Ratio (NLR), simple, rapidly assessed markers from the …