[HTML][HTML] Stem cell membrane-coated abiotic nanomaterials for biomedical applications

I Ferreira-Faria, S Yousefiasl, A Macário-Soares… - Journal of controlled …, 2022 - Elsevier
Nanoscale materials have been extensively employed for diagnostic and therapeutic
purposes. However, the developed nanosystems still suffer from some limitations, namely …

HGF and MET: from brain development to neurological disorders

C Desole, S Gallo, A Vitacolonna… - Frontiers in Cell and …, 2021 - frontiersin.org
Hepatocyte growth factor (HGF) and its tyrosine kinase receptor, encoded by the MET
cellular proto-oncogene, are expressed in the nervous system from pre-natal development …

Sumoylation in physiology, pathology and therapy

U Sahin, H de Thé, V Lallemand-Breitenbach - Cells, 2022 - mdpi.com
Sumoylation is an essential post-translational modification that has evolved to regulate
intricate networks within emerging complexities of eukaryotic cells. Thousands of target …

Functionalization of electrospun nanofibers and fiber alignment enhance neural stem cell proliferation and neuronal differentiation

MC Amores de Sousa, CAV Rodrigues… - … in Bioengineering and …, 2020 - frontiersin.org
Neural stem cells (NSCs) have the potential to generate the cells of the nervous system and,
when cultured on nanofiber scaffolds, constitute a promising approach for neural tissue …

Stem cell therapies for progressive multiple sclerosis

JA Smith, AM Nicaise, RB Ionescu, R Hamel… - Frontiers in cell and …, 2021 - frontiersin.org
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
characterized by demyelination and axonal degeneration. MS patients typically present with …

[HTML][HTML] The role of autophagy in the metabolism and differentiation of stem cells

M Adelipour, LR Saleth, S Ghavami… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Autophagy is a very well-coordinated intracellular process that maintains cellular
homeostasis under basal conditions by removing unnecessary or dysfunctional components …

Detrimental effects of alcohol-induced inflammation on brain health: from neurogenesis to neurodegeneration

SK Anand, MH Ahmad, MR Sahu, R Subba… - Cellular and Molecular …, 2023 - Springer
Alcohol consumption is known to cause several brain anomalies. The pathophysiological
changes associated with alcohol intoxication are mediated by various factors, most notable …

The role of microRNAs in neurobiology and pathophysiology of the hippocampus

SK Rashidi, A Kalirad, S Rafie, E Behzad… - Frontiers in molecular …, 2023 - frontiersin.org
MicroRNAs (miRNAs) are short non-coding and well-conserved RNAs that are linked to
many aspects of development and disorders. MicroRNAs control the expression of genes …

[HTML][HTML] Recent advances in genome editing of stem cells for drug discovery and therapeutic application

J Lee, D Bayarsaikhan, G Bayarsaikhan, JS Kim… - Pharmacology & …, 2020 - Elsevier
Genome engineering technologies right from viral vector-mediated to protein-based editing—
which include zinc finger nucleases, TALENs, and CRISPR/Cas systems—have been …

Mechanisms underlying the effect of voluntary running on adult hippocampal neurogenesis

Y Gao, M Syed, X Zhao - Hippocampus, 2023 - Wiley Online Library
Adult hippocampal neurogenesis is important for preserving learning and memory‐related
cognitive functions. Physical exercise, especially voluntary running, is one of the strongest …