MAS-related G protein-coupled receptors (GPCRs) of subfamily X, designated MRGPRX,
are primate-specific orphan receptors that belong to the δ-branch of rhodopsin-like, class A …

Cornea is an avascular and transparent tissue that focuses light on retina. Cornea is
supported by the corneal‐endothelial layer through regulation of hydration homeostasis …

The Drosophila corneal lens is entirely composed of chitin and other apical extracellular
matrix components, and it is not known how it acquires the biconvex shape that enables it to …

Bulk RNA sequencing of a tissue captures the gene expression profile from all cell types
combined. Single-cell RNA sequencing identifies discrete cell-signatures based on …

Aim To generate human embryonic stem cell derived corneal endothelial cells (hESC-
CECs) for transplantation in patients with corneal endothelial dystrophies. Materials and …

The advent of cell culture-based methods for the establishment and expansion of human
corneal endothelial cells (CEnC) has provided a source of transplantable corneal …

The corneal endothelium plays a primary role in maintaining corneal homeostasis and
clarity and must be surgically replaced with allogenic donor corneal endothelium in the …

Objective In order to provide regenerative therapy for millions of patients suffering from
corneal blindness globally, we derived corneal endothelial cell substitute (CECSi) cells from …

The cornea forms the front window of the eye, enabling the transmission of light to the retina
through a crystalline lens. Many disorders of the cornea lead to partial or total blindness, and …

Corneal endothelial disorders collectively represent a significant healthcare burden in most
developed nations, and corneal transplantation is currently the only treatment available for …