Cancer has become a global health issue and liquid biopsy has emerged as a non-invasive
tool for various applications. In cancer, circulating tumor DNA (ctDNA) can be detected from …

Massively parallel sequencing technologies have long been used in both basic research
and clinical routine. The recent introduction of digital sequencing has made previously …

Liquid biopsies are the detection of molecular information in fluids from patients with cancer.
In colorectal cancer (CRC), the most promising liquid biopsy strategy is the use of circulating …

The equine bloodworm, Strongylus vulgaris, is a common and highly pathogenic parasite in
horses due to its migratory life cycle involving the intestinal arteries. Current diagnostic …

Unique molecular identifiers are random oligonucleotide sequences that remove PCR
amplification biases. However, the impact that PCR associated sequencing errors have on …

Background Obtaining sufficient tumor tissue for genomic profiling is challenging in
pancreaticobiliary cancer (PBCA). We determined the utility of molecular barcoding (MB) of …

Background: Although next generation sequencing (NGS) has been adopted as an essential
diagnostic tool in various diseases, NGS errors have been the most serious problem in …

Objectives Pancreatic cancer (PC) has a poor prognosis and limited treatment options.
Liquid biopsy, which analyzes circulating tumor DNA (ctDNA) in blood, holds promise for …

Whole genome sequencing (WGS) at high-depth (30X) allows the accurate discovery of
variants in the coding and non-coding DNA regions and helps elucidate the genetic …

Abstract Unique Molecular Identifiers (UMIs) are random oligonucleotide sequences that
remove PCR amplification biases. However, the impact that PCR associated sequencing …