Alcoholic liver disease: alcohol metabolism, cascade of molecular mechanisms, cellular targets, and clinical aspects

R Teschke - Biomedicines, 2018 - mdpi.com
Alcoholic liver disease is the result of cascade events, which clinically first lead to alcoholic
fatty liver, and then mostly via alcoholic steatohepatitis or alcoholic hepatitis potentially to …

[HTML][HTML] Permeability across lipid membranes

W Shinoda - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2016 - Elsevier
Molecular permeation through lipid membranes is a fundamental biological process that is
important for small neutral molecules and drug molecules. Precise characterization of free …

Permeability of the blood–brain barrier: molecular mechanism of transport of drugs and physiologically important compounds

CW Fong - The Journal of membrane biology, 2015 - Springer
A new molecular model for the permeability of drugs and other physiologically important
compounds to cross the blood–brain barrier has been developed. Permeability (log PS) is …

Identifying extracellular vesicle populations from single cells

JM Nikoloff, MA Saucedo-Espinosa… - Proceedings of the …, 2021 - National Acad Sciences
Extracellular vesicles (EVs) are constantly secreted from both eukaryotic and prokaryotic
cells. EVs, including those referred to as exosomes, may have an impact on cell signaling …

Development of a microfluidic-based post-treatment process for size-controlled lipid nanoparticles and application to siRNA delivery

N Kimura, M Maeki, Y Sato, A Ishida… - … applied materials & …, 2020 - ACS Publications
Microfluidic methodologies for preparation of lipid nanoparticles (LNPs) based on an
organic solvent injection method enable precise size control of the LNPs. After preparation …

Merits and advances of microfluidics in the pharmaceutical field: design technologies and future prospects

A Maged, R Abdelbaset, AA Mahmoud… - Drug delivery, 2022 - Taylor & Francis
Microfluidics is used to manipulate fluid flow in micro-channels to fabricate drug delivery
vesicles in a uniform tunable size. Thanks to their designs, microfluidic technology provides …

High‐Precision Synthesis of RNA‐Loaded Lipid Nanoparticles for Biomedical Applications

H Seo, L Jeon, J Kwon, H Lee - Advanced Healthcare …, 2023 - Wiley Online Library
The recent development of RNA‐based therapeutics in delivering nucleic acids for gene
editing and regulating protein translation has led to the effective treatment of various …

Novel microfluidic swirl mixers for scalable formulation of curcumin loaded liposomes for cancer therapy

R Xu, MA Tomeh, S Ye, P Zhang, S Lv, R You… - International Journal of …, 2022 - Elsevier
Liposomes have been widely used in nanomedicine for the delivery of hydrophobic and
hydrophilic anticancer agents. The most common applications of these formulations are …

Phospholipid membrane formation templated by coacervate droplets

F Pir Cakmak, AM Marianelli, CD Keating - Langmuir, 2021 - ACS Publications
We report the formation of coacervate-supported phospholipid membranes by hydrating a
dried lipid film in the presence of coacervate droplets. Coacervate-supported membranes …

[HTML][HTML] A química dos saneantes em tempos de COVID-19: você sabe como isso funciona?

MLSO Lima, RKS Almeida, FSA da Fonseca… - Química …, 2020 - SciELO Brasil
In December 2019, the first case of severe acute respiratory syndrome (COVID-19), caused
by the new coronavirus (SARS-CoV-2) was reported and the disease was declared as a …