This paper is the forty-fourth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Background High potency synthetic opioids like fentanyl have continued to replace or
contaminate the supply of illicit drugs in North America, with fentanyl test strips (FTSs) often …

Background Opioid use has been increasing at alarming rates over the past 15 years, yet
uptake of medication for opioid use disorder (MOUD) remains low. Much of the research on …

Background Across the world, substance use remains a public health problem and a
significant contributor to morbidity, mortality, and reduced quality of life. Globally, the …

The opioid overdose crisis in the United States has led to thousands of lost lives and
thousands more people struggling with opioid dependence. Disease modeling allows …