Quorum sensing for population-level control of bacteria and potential therapeutic applications

S Wu, J Liu, C Liu, A Yang, J Qiao - Cellular and Molecular Life Sciences, 2020 - Springer
Quorum sensing (QS), a microbial cell-to-cell communication process, dynamically regulates
a variety of metabolism and physiological activities. In this review, we provide an update on …

Predictive biology: modelling, understanding and harnessing microbial complexity

AJ Lopatkin, JJ Collins - Nature Reviews Microbiology, 2020 - nature.com
Predictive biology is the next great chapter in synthetic and systems biology, particularly for
microorganisms. Tasks that once seemed infeasible are increasingly being realized such as …

Synthetic biology for manipulating quorum sensing in microbial consortia

K Stephens, WE Bentley - Trends in microbiology, 2020 - cell.com
Bacteria exist as communities in diverse multispecies environments. Quorum sensing, a
process for cell–cell communication, allows individual bacteria to glean information about …

Modulation of microbial community dynamics by spatial partitioning

F Wu, Y Ha, A Weiss, M Wang, J Letourneau… - Nature chemical …, 2022 - nature.com
Microbial communities inhabit spatial architectures that divide a global environment into
isolated or semi-isolated local environments, which leads to the partitioning of a microbial …

Emerging strategies for engineering microbial communities

R Tsoi, Z Dai, L You - Biotechnology advances, 2019 - Elsevier
From biosynthesis to bioremediation, microbes have been engineered to address a variety
of biotechnological applications. A promising direction in these endeavors is harnessing the …

Quorum sensing communication: molecularly connecting cells, their neighbors, and even devices

S Wang, GF Payne, WE Bentley - Annual review of chemical …, 2020 - annualreviews.org
Quorum sensing (QS) is a molecular signaling modality that mediates molecular-based cell–
cell communication. Prevalent in nature, QS networks provide bacteria with a method to …

Towards an ecosystem model of infectious disease

JM Hassell, T Newbold, AP Dobson… - Nature ecology & …, 2021 - nature.com
Increasingly intimate associations between human society and the natural environment are
driving the emergence of novel pathogens, with devastating consequences for humans and …

Autoencoder neural networks enable low dimensional structure analyses of microbial growth dynamics

Y Baig, HR Ma, H Xu, L You - Nature Communications, 2023 - nature.com
The ability to effectively represent microbiome dynamics is a crucial challenge in their
quantitative analysis and engineering. By using autoencoder neural networks, we show that …

Ecological theory of mutualism: Robust patterns of stability and thresholds in two‐species population models

KRS Hale, FS Valdovinos - Ecology and Evolution, 2021 - Wiley Online Library
Mutualisms are ubiquitous in nature, provide important ecosystem services, and involve
many species of interest for conservation. Theoretical progress on the population dynamics …

Engineered microbial consortia: strategies and applications

KE Duncker, ZA Holmes, L You - Microbial Cell Factories, 2021 - Springer
Many applications of microbial synthetic biology, such as metabolic engineering and
biocomputing, are increasing in design complexity. Implementing complex tasks in single …