The importance of glutamate, glycine, and γ-aminobutyric acid transport and regulation in manganese, mercury and lead neurotoxicity

VA Fitsanakis, M Aschner - Toxicology and applied pharmacology, 2005 - Elsevier
Historically, amino acids were studied in the context of their importance in protein synthesis.
In the 1950s, the focus of research shifted as amino acids were recognized as putative …

Beyond the behavioural phenotype: Uncovering mechanistic foundations in aquatic eco-neurotoxicology

D Wlodkowic, A Bownik, C Leitner, D Stengel… - Science of The Total …, 2022 - Elsevier
During the last decade, there has been an increase in awareness of how anthropogenic
pollution can alter behavioural traits of diverse aquatic organisms. Apart from understanding …

Neonicotinoid insecticides inhibit cholinergic neurotransmission in a molluscan (Lymnaea stagnalis) nervous system

Á Vehovszky, A Farkas, A Ács, O Stoliar, A Székács… - Aquatic Toxicology, 2015 - Elsevier
Neonicotinoids are highly potent and selective systemic insecticides, but their widespread
use also has a growing impact on non-target animals and contaminates the environment …

Noninvasive electrophysiology: emerging prospects in aquatic neurotoxicity testing

DL Tomasello, D Wlodkowic - Environmental science & …, 2022 - ACS Publications
The significance of neurotoxicological risks associated with anthropogenic pollution is
gaining increasing recognition worldwide. In this regard, perturbations in behavioral traits …

Differing effects of toxicants (methylmercury, inorganic mercury, lead, amyloid β, and rotenone) on cultured rat cerebrocortical neurons: differential expression of rho …

M Fujimura, F Usuki - Toxicological Sciences, 2012 - academic.oup.com
Abstract Methylmercury (MeHg), inorganic mercury (IHg), lead (Pb), amyloid-β peptide (Aβ),
and rotenone (RTN) are well-known toxicants. Here, we demonstrate that these five …

Invertebrates in neurotoxicology

J Salanki - Acta Biologica Hungarica, 2000 - Springer
Due to the relative simplicity of their nervous system, invertebrate animals were widely used
in the past decades for studying the processes of excitability at membrane level, as well as …

Effect of inorganic and organic tin compounds on ACh-and voltage-activated Na currents

J Györi, O Platoshyn, DO Carpenter… - Cellular and Molecular …, 2000 - Springer
Inorganic tin and organotin compounds, occurring in aquatic ecosystems, are toxic and can
cause behavioral abnormalities in living organisms. To determine the possible neuronal …

Altered electrophysiological characteristics of developing rat cortical neurones after chronic methylmercury chloride treatment

I Világi, J Dóczi, I Banczerowski-Pelyhe - International Journal of …, 2000 - Elsevier
The effect of methylmercury chloride on the excitability of developing cortical neurons was
tested. Methylmercury was administered in the drinking water to pregnant rats during …

Mercuric(II) chloride modulates single-channel properties of carbachol-activated Cl channels in cultured neurons ofAplysia californica

M Fejtl, J Györi, DO Carpenter - Cellular and molecular neurobiology, 1994 - Springer
The effect of mercuric (II) chloride on kinetic parameters of carbacholactivated single
chloride channels were studied in cultured neurons of the marine mollusk, Aplysia …

Cadmium ions modulate GABA induced currents in molluscan neurons

G Molnár, J Győri, J Salánki, K S.-Rózsa - Acta Biologica Hungarica, 2002 - Springer
The effect of Cd 2+, as one of the most widespread toxic environmental pollutants, was
studied on γ-aminobutyric acid (GABA) evoked responses of identified neurons in the central …