Polycystic ovary syndrome

AE Joham, RJ Norman, E Stener-Victorin… - The lancet Diabetes & …, 2022 - thelancet.com
Polycystic ovary syndrome (PCOS) affects 5–18% of women, and is a reproductive,
metabolic, and psychological condition with impacts across the lifespan. The cause is …

Epigenetic inheritance of polycystic ovary syndrome—challenges and opportunities for treatment

E Stener-Victorin, Q Deng - Nature Reviews Endocrinology, 2021 - nature.com
Polycystic ovary syndrome (PCOS) is the main cause of female infertility worldwide and is
associated with a substantially increased lifetime risk of comorbidities, including type 2 …

Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome

E Stener-Victorin, V Padmanabhan… - Endocrine …, 2020 - academic.oup.com
More than 1 out of 10 women worldwide are diagnosed with polycystic ovary syndrome
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …

Prenatal androgen exposure and transgenerational susceptibility to polycystic ovary syndrome

S Risal, Y Pei, H Lu, M Manti, R Fornes, HP Pui… - Nature Medicine, 2019 - nature.com
How obesity and elevated androgen levels in women with polycystic ovary syndrome
(PCOS) affect their offspring is unclear. In a Swedish nationwide register-based cohort and a …

Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood

B Tata, NEH Mimouni, AL Barbotin, SA Malone… - Nature medicine, 2018 - nature.com
Polycystic ovary syndrome (PCOS) is the main cause of female infertility worldwide and
corresponds with a high degree of comorbidities and economic burden. How PCOS is …

Pregnancy complications in women with polycystic ovary syndrome

S Palomba, MA De Wilde, A Falbo… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND The great majority of studies performed so far concerning women
diagnosed with polycystic ovary syndrome (PCOS) have focused on diagnosis, menstrual …

Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome

S Vannuccini, VL Clifton, IS Fraser… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND Reproductive disorders and infertility are associated with the risk of
obstetric complications and have a negative impact on pregnancy outcome. Affected …

Polycystic ovary syndrome throughout a woman's life

J Bellver, L Rodríguez-Tabernero, A Robles… - Journal of assisted …, 2018 - Springer
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among
reproductive-aged women and the main cause of infertility due to anovulation. However, this …

Targeting STAT3 signaling pathway in colorectal cancer

AN Gargalionis, KA Papavassiliou, AG Papavassiliou - Biomedicines, 2021 - mdpi.com
Signal transducer and activator of transcription 3 (STAT3) is a critical transcription factor that
has been firmly associated with colorectal cancer (CRC) initiation and development. STAT3 …

Steroid hormones and pregnancy

N Noyola-Martínez, A Halhali… - Gynecological …, 2019 - Taylor & Francis
Pregnancy is associated with physiological adjustments in order to allow adequate growth
and fetal development. In particular, steroids are necessary to maintain in balance …