Early detection of subclinical atherosclerosis is important to reduce patients' cardiovascular
risk. However, current diagnostic strategy focusing on traditional risk factors or using risk …

An individual participant data meta-analysis was conducted in the data of 14 673 Japanese
participants without a history of cardiovascular disease (CVD) to examine the association of …

Townsend et al Vascular Research on Arterial Stiffness 699 pressure, blood flow, and
arterial diameter change with each heartbeat. In addition to the passive mechanical …

Physical inactivity is one of the most prevalent major health risk factors, with 8 in 10 US
adults not meeting aerobic and muscle-strengthening guidelines, and is associated with a …

While risk scores are invaluable tools for adapted preventive strategies, a significant gap
exists between predicted and actual event rates. Additional tools to further stratify the risk of …

Objectives: The goal of this study was to determine whether aortic pulse wave velocity
(aPWV) improves prediction of cardiovascular disease (CVD) events beyond conventional …

Among age-related diseases, cardiovascular and cerebrovascular diseases are major
causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age …

Stiffness of elastic arteries like the aorta predicts cardiovascular risk. By directly reflecting
arterial stiffness, having the best predictive value for cardiovascular outcome and the ease of …

We tested the hypothesis that supplementation of nicotinamide mononucleotide (NMN), a
key NAD+ intermediate, increases arterial SIRT 1 activity and reverses age‐associated …

Context Vascular stiffness increases with advancing age and is a major risk factor for age-
related morbidity and mortality. Vascular stiffness and blood pressure pulsatility are related; …