Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …

The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Parthanatos-associated apoptosis-inducing factor (AIF) nuclease (PAAN), also known as
macrophage migration inhibitor factor (MIF), is a member of the PD-D/E (X) K nucleases that …

Sepsis and septic shock are among the leading causes of death in intensive care units
worldwide. Numerous studies on their pathophysiology have revealed an imbalance in the …

The innate immune system in drosophila and mammals senses the invasion of
microorganisms using the family of Toll receptors, stimulation of which initiates a range of …

Inflammation is a complex set of interactions among soluble factors and cells that can arise
in any tissue in response to traumatic, infectious, post-ischaemic, toxic or autoimmune injury …

Sepsis is a condition that results from a harmful or damaging host response to infection.
Many of the components of the innate immune response that are normally concerned with …

For more than a quarter of a century, macrophage migration inhibitory factor (MIF) has been
a mysterious cytokine. In recent years, MIF has assumed an important role as a pivotal …

Pancreatic cancers with aberrant expression of macrophage migration inhibitory factor (MIF)
are particularly aggressive. To identify key signaling pathways that drive disease …

Bacterial lipopolysaccharides (LPS) are the major outer surface membrane components
present in almost all Gram-negative bacteria and act as extremely strong stimulators of …