Methylation of DNA and of histone 3 at Lys 9 (H3K9) are highly correlated with gene
silencing in eukaryotes from fungi to humans. Both of these epigenetic marks need to be …

Plants as sessile organisms have remarkable developmental plasticity ensuring heir
continuous adaptation to the environment. An extreme example is somatic embryogenesis …

DNA methylation occurs in CG and non-CG sequence contexts. Non-CG methylation is
abundant in plants and is mediated by CHROMOMETHYLASE (CMT) and DOMAINS …

Programmed constitutive heterochromatin silencing is essential for eukaryotic genome
regulation, yet the initial step of this process is ambiguous. A large proportion of R-loops …

Cytosine methylation is involved in various biological processes such as silencing of
transposable elements (TEs) and imprinting. Multiple pathways regulate DNA methylation in …

Pathogen recognition by plants results in the activation of signaling pathways that induce
defense reactions. There is growing evidence indicating that epigenetic mechanisms directly …

Epigenetic mechanisms, which involve DNA and histone modifications, result in the
heritable silencing of genes without a change in their coding sequence. The study of human …

In the metazoan germline, piwi proteins and associated piwi-interacting RNAs (piRNAs)
provide a defense system against the expression of transposable elements. In the …

Histone methylation plays a fundamental role in regulating diverse developmental
processes and is also involved in silencing repetitive sequences in order to maintain …

Transposable elements (TEs) are mobile parasitic sequences that have been repeatedly
coopted during evolution to generate new functions and rewire gene regulatory networks …