Discerning the prospects of miRNAs as a multi-target therapeutic and diagnostic for alzheimer's disease
D Bhatnagar, S Ladhe, D Kumar - Molecular Neurobiology, 2023 - Springer
Although over the last few decades, numerous attempts have been made to halt Alzheimer's
disease (AD) progression and mitigate its symptoms, only a few have been proven …
disease (AD) progression and mitigate its symptoms, only a few have been proven …
Inhibition of virus replication by RNA interference
J Haasnoot, D Cupac, B Berkhout - Journal of biomedical science, 2003 - Springer
RNA interference (RNAi) is a sequence-specific gene-silencing mechanism in eukaryotes,
which is believed to function as a defence against viruses and transposons. Since its …
which is believed to function as a defence against viruses and transposons. Since its …
FIE and CURLY LEAF polycomb proteins interact in the regulation of homeobox gene expression during sporophyte development
Summary The Arabidopsis FERTILIZATION‐INDEPENDENT ENDOSPERM (FIE) polycomb
group (PcG) protein, a WD40 homologue of Drosophila extra sex comb (ESC), regulates …
group (PcG) protein, a WD40 homologue of Drosophila extra sex comb (ESC), regulates …
Compositions for RNA interference and methods of use thereof
The present invention provides compositions for RNA interference and methods of use
thereof. In particular, the invention provides single-stranded small interfering RNAs …
thereof. In particular, the invention provides single-stranded small interfering RNAs …
[HTML][HTML] Double-stranded RNA (dsRNA) technology to control forest insect pests and fungal pathogens: challenges and opportunities
K Singewar, M Fladung - Functional & Integrative Genomics, 2023 - Springer
Climate change alters the seasonal synchronization between plants and respective pests
plus pathogens. The geographical infiltration helps to shift their hosts, resulting in novel …
plus pathogens. The geographical infiltration helps to shift their hosts, resulting in novel …
RNA interference: past, present and future
TN Campbell, FYM Choy - Current issues in molecular biology, 2005 - mdpi.com
RNA interference (RNAi) is the sequence-specific gene silencing induced by double-
stranded RNA. RNAi is mediated by 21-23 nucleotide small interfering RNAs (siRNAs) …
stranded RNA. RNAi is mediated by 21-23 nucleotide small interfering RNAs (siRNAs) …
RNAi: antiviral therapy against dengue virus
Dengue virus infection has become a global threat affecting around 100 countries in the
world. Currently, there is no licensed antiviral agent available against dengue. Thus, there is …
world. Currently, there is no licensed antiviral agent available against dengue. Thus, there is …
Suppression of Thrips palmi population by spray-on application of dsRNA targeting V-ATPase-B
The RNA interference (RNAi)-based gene silencing technique has enormous potential as a
non-chemical and eco-friendly alternative to hazardous pesticides. This study reports a …
non-chemical and eco-friendly alternative to hazardous pesticides. This study reports a …
RNA interference mediating small RNA molecules
T Tuschl, SM Elbashir, W Lendeckel - US Patent 8,362,231, 2013 - Google Patents
Double-stranded RNA (dsRNA) induces sequence-specific post-transcriptional gene
silencing in many organisms by a process known as RNA interference (RNAi). Using a …
silencing in many organisms by a process known as RNA interference (RNAi). Using a …
RNA interference in designing transgenic crops
N Ali, SK Datta, K Datta - GM crops, 2010 - Taylor & Francis
RNA interference (RNAi) is a sequence specific gene silencing mechanism, triggered by the
introduction of dsRNA leading to mRNA degradation. It helps in switching on and off the …
introduction of dsRNA leading to mRNA degradation. It helps in switching on and off the …