Major depressive disorder (MDD), also referred to as depression, is one of the most common
psychiatric disorders with a high economic burden. The etiology of depression is still not …

Depression is one of the leading causes of disability, and, if left unmanaged, it can increase
the risk for suicide. The evidence base on the determinants of depression is fragmented …

Major depressive disorder (MDD) is a heterogeneous disease affecting one out of five
individuals and is the leading cause of disability worldwide. Presently, MDD is considered a …

Brain derived neurotrophic factor (BDNF) has multiple biological functions which are
mediated by the activation of two receptors, tropomyosin receptor kinase B (TrkB) receptor …

Brain-derived nerve factor (BDNF), through TrkB receptor activation, is an important
modulator for many different physiological and pathological functions in the nervous system …

Brain-derived neurotrophic factor is an extensively studied neurotrophin implicated in the
pathology of multiple neurodegenerative and psychiatric disorders including, but not limited …

Depression is a common neuropsychiatric disorder characterized by persistent depressed
mood and causes serious socioeconomic burden worldwide. Hyperactivity of the …

Brain-derived neurotrophic factor (BDNF) and its precursor, proBDNF, are known to
significantly contribute to brain homeostasis, neuroplasticity, and neuronal remodeling …

Depression and anxiety have been reported as the major neuropsychiatric consequences
following stroke. Minocycline, a neuroprotective drug has minimized depressive symptoms …

Abstract Allopregnanolone (3α, 5α-tetrahydroprogesterone; pharmaceutical formulation:
brexanolone) is a neurosteroid that has recently been approved for the treatment of …