MicroRNAs (miRNAs) have emerged as a class of regulatory RNAs in host–pathogen
interactions. Aberrant miRNA expression seems to play a central role in the pathology of …

Annual influenza vaccinations are currently recommended for all individuals 6 months and
older. Antibodies induced by vaccination are an important mechanism of protection against …

Proteases drive the life cycle of all proteins, ensuring the transportation and activation of
newly minted, would-be proteins into their functional form while recycling spent or unneeded …

Influenza is a global health concern, causing death, morbidity, and economic losses.
Chemotherapeutics that target influenza virus are available; however, rapid emergence of …

A growing body of evidence suggests the non-protein coding human genome is of vital
importance for human cell function. Besides small RNAs, the diverse class of long non …

Influenza A virus (IAV) infection causes seasonal epidemics of contagious respiratory illness
that causes substantial morbidity and some mortality. Regular vaccination is the principal …

Despite evidence for participation in the host response to infection, the roles of many long
non-coding RNAs (lncRNAs) remain unknown. Therefore, the aims of this study were to …

Background With concerns about the disastrous health and economic consequences
caused by the influenza pandemic, comprehensively understanding the global host …

Vaccine manufacturing costs prevent a significant portion of the world's population from
accessing protection from vaccine-preventable diseases. To enhance vaccine production at …

Human protein kinases (HPKs) have profound effects on cellular responses. To better
understand the role of HPKs and the signaling networks that influence influenza virus …