Effects and mechanisms of curcumin for the prevention and management of cancers: An updated review

ZJ Yang, SY Huang, DD Zhou, RG Xiong, CN Zhao… - Antioxidants, 2022 - mdpi.com
Cancer is the leading cause of death in the world. Curcumin is the main ingredient in
turmeric (Curcuma longa L.), and is widely used in the food industry. It shows anticancer …

From antimicrobial to anticancer peptides. A review

D Gaspar, AS Veiga, MARB Castanho - Frontiers in microbiology, 2013 - frontiersin.org
Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many
organisms. Although AMPs have been essentially studied and developed as potential …

Nanomedicine for targeted cancer therapy: towards the overcoming of drug resistance

A Shapira, YD Livney, HJ Broxterman… - Drug resistance updates, 2011 - Elsevier
Anticancer drug resistance almost invariably emerges and poses major obstacles towards
curative therapy of various human malignancies. In the current review we will distinguish …

The role of extracellular vesicles in the transfer of drug resistance competences to cancer cells

CPR Xavier, DC Belisario, R Rebelo, YG Assaraf… - Drug Resistance …, 2022 - Elsevier
Drug resistance remains a major hurdle to successful cancer treatment, being accountable
for approximately 90% of cancer-related deaths. In the past years, increasing attention has …

Biophysics of cell membrane lipids in cancer drug resistance: Implications for drug transport and drug delivery with nanoparticles

C Peetla, S Vijayaraghavalu, V Labhasetwar - Advanced drug delivery …, 2013 - Elsevier
In this review, we focus on the biophysics of cell membrane lipids, particularly when cancers
develop acquired drug resistance, and how biophysical changes in resistant cell membrane …

Enzymatic metabolism of flavonoids by gut microbiota and its impact on gastrointestinal cancer

RK Al-Ishaq, A Liskova, P Kubatka, D Büsselberg - Cancers, 2021 - mdpi.com
Simple Summary Flavonoid's consumption is reported to impact GI cancer progression
positively. As 90% of flavonoids consumed, undergo metabolism and conversion by the …

MicroRNA dysregulation in gastric cancer: a new player enters the game

WKK Wu, CW Lee, CH Cho, D Fan, K Wu, J Yu… - Oncogene, 2010 - nature.com
Gastric carcinogenesis is a multistep process involving genetic and epigenetic alteration of
protein-coding proto-oncogenes and tumor-suppressor genes. Recent discoveries have …

Thiazolidine-2, 4-diones: Progress towards multifarious applications

VS Jain, DK Vora, CS Ramaa - Bioorganic & medicinal chemistry, 2013 - Elsevier
The promising activity shown by compounds containing thiazolidine-2, 4-dione nucleus in
numerous categories such as anti-hyperglycaemics, aldose reductase inhibitors, anti …

Anti-tumor drug discovery based on natural product β-elemene: Anti-tumor mechanisms and structural modification

Z Bai, C Yao, J Zhu, Y Xie, XY Ye, R Bai, T Xie - Molecules, 2021 - mdpi.com
Natural products are important sources for drug discovery, especially anti-tumor drugs. β-
Elemene, the prominent active ingredient extract from the rhizome of Curcuma wenyujin, is a …

Mechanisms of resistance to chemotherapy in gastric cancer

JJG Marin, R Al-Abdulla, E Lozano… - Anti-Cancer Agents …, 2016 - ingentaconnect.com
Although surgical resection is the standard curative therapy for gastric cancer, these tumors
are often diagnosed at an advanced stage, when surgery is not recommended. Alternative …