Cancer is the second cause of death in 2015, and it has been estimated to surpass heart
diseases as the leading cause of death in the next few years. Several mechanisms are …

Human SERPINB3 and SERPINB4 are evolutionary duplicated serine/cysteine protease
inhibitors. Genomic analysis indicates that these paralogous genes were encoded from …

Cervical cancer represents one of the most important malignancies among women
worldwide. Current therapeutic approaches for cervical cancer are reported not only to be …

Objective. To systematically evaluate the significance of squamous cell carcinoma antigen
(SCC‐Ag) in the prognosis of cervical cancer. Methods. Literature from Pubmed, Embase …

Aims The aim of the study was to evaluate the role of Serpin B3/B4 in advanced idiopathic
pulmonary fibrosis (IPF) patients, mainly focusing on epithelial proliferation. Methods Lungs …

To clarify the synergistic influence of human papillomavirus (HPV) status and squamous cell
carcinoma antigen (SCCA) mRNA expression on head and neck squamous cell carcinoma …

BACKGROUND: Cervical cancer is the second most common malignancy in women, with
nearly half a million new cases diagnosed each year worldwide. The authors' recent studies …

Maspin, a member of the serpin family of serine protease inhibitors, was originally identified
as a tumor suppressor that is expressed in normal mammary epithelial cells but is reduced …

Serine protease inhibitors (SERPINs) appear to be ubiquitously expressed in a variety of
species and play important roles in pivotal physiological processes such as angiogenesis …

SerpinB3 is a serine protease inhibitor that plays a relevant role in disease progression and
cancer by increasing fibrosis, cell proliferation, and invasion, besides conferring resistance …