Ferroptosis is a newly discovered type of cell death that differs from traditional apoptosis and
necrosis and results from iron‐dependent lipid peroxide accumulation. Ferroptotic cell death …

Ferroptosis is a process driven by accumulated iron-dependent lipid ROS that leads to cell
death, which is a distinct regulated cell death comparing to other cell death. The lethal …

Ferroptosis is a form of nonapoptotic cell death for which key regulators remain unknown.
We sought a common mediator for the lethality of 12 ferroptosis-inducing small molecules …

Little is known about the regulation of nonapoptotic cell death. Using massive insertional
mutagenesis of haploid KBM7 cells we identified nine genes involved in small-molecule …

Chromones are a group of naturally occurring compounds that are ubiquitous in nature,
especially in plants. The word chromone is derived from the Greek word chroma, meaning …

Ferroptosis is a recently recognized form of regulated cell death. It is characterized
morphologically by the presence of smaller than normal mitochondria with condensed …

Highlights•Colchicine binding site inhibitors (CBSIs) emerge as new generations of tubulin
inhibitors.•CBSIs are less susceptible to multidrug resistance than FDA-approved tubulin …

Ferroptosis belongs to a novel form of regulated cell death. It is characterized by iron
dependence, destruction of intracellular redox balance and non-apoptosis. And cellular …

Kidney cancer is a cancer with an increasing incidence in recent years. Clear cell renal cell
carcinoma (ccRCC) accounts for up to 80% of all kidney cancers. The understanding of the …

Ferroptosis is a recently identified nonapoptotic form of cell death whose major markers are
iron dependence and accumulation of lipid reactive oxygen species, accompanied by …