Carbohydrates are fundamental molecules involved in nearly all aspects of lives, such as
being involved in formating the genetic and energy materials, supporting the structure of …

Glycoside trimming enzymes are crucially important in a broad range of metabolic pathways,
including glycoprotein and glycolipid processing and carbohydrate digestion in the intestinal …

Carbon–carbon bond formation is the key reaction for organic synthesis to construct the
carbon framework of organic molecules. The review gives a selection of biocatalytic C–C …

Glycoside hydrolases, the enzymes responsible for hydrolysis of the glycosidic bond in di-,
oligo-and polysaccharides, and glycoconjugates, are ubiquitous in Nature and fundamental …

Carbohydrate chemistry constitutes today a “multifaceted” discipline strongly connected with
organic, pharmaceutical, and medicinal chemistry. 1 Carbohydrates are important …

Valienamine is a valuable building block for active pharmaceuticals and agrochemicals
because of its aminocyclitol structure and glucosidase inhibitory activity. Straightforward …

A simple, efficient and practical procedure for the Biginelli reaction using strontium (II) triflate
[Sr (OTf) 2] as a novel catalyst is described under solvent-free conditions in high yields. The …

Chalcones 1–20, a new class of glycosidase inhibitors, were synthesized, and their
glycosidase inhibitory activities were investigated. Non-aminochalcones 1–12 had no …

The huge increase in type 2 diabetes is a burden worldwide. Many marketed compounds do
not address relevant aspects of the disease; they may already compensate for defects in …

The number of people with diabetes is expected to rise from the current estimated 150
million to 220 million in 2010 and 300 million in 2025, and 90% is Type 2 diabetes or non …