[HTML][HTML] Complement and COVID-19: Three years on, what we know, what we don't know, and what we ought to know

WM Zelek, RA Harrison - Immunobiology, 2023 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus was identified in
China in 2019 as the causative agent of COVID-19, and quickly spread throughout the …

[HTML][HTML] Complement-mediated microvascular injury and thrombosis in the pathogenesis of severe COVID-19: A review

P Gianni, M Goldin, S Ngu, S Zafeiropoulos… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) causes acute microvascular thrombosis in
both venous and arterial structures which is highly associated with increased mortality. The …

[HTML][HTML] Identification of novel antiviral drug candidates using an optimized SARS-CoV-2 phenotypic screening platform

D Bojkova, P Reus, L Panosch, M Bechtel… - Iscience, 2023 - cell.com
Reliable, easy-to-handle phenotypic screening platforms are needed for the identification of
anti-SARS-CoV-2 compounds. Here, we present caspase 3/7 activity as a readout for …

Intertwined pathways of complement activation command the pathogenesis of lupus nephritis

A Satyam, R Hisada, R Bhargava, MG Tsokos… - Translational …, 2022 - Elsevier
The complement system is involved in the origin of autoimmunity and systemic lupus
erythematosus. Both genetic deficiency of complement components and excessive …

Autophagy-associated HMGB-1 as a novel potential circulating non-invasive diagnostic marker for detection of Urothelial Carcinoma of Bladder

A Singh, N Gupta, H Khandakar, S Kaushal… - Molecular and Cellular …, 2022 - Springer
Urothelial carcinoma of bladder (UBC), a highly prevalent urological malignancy associated
with high mortality and recurrence rate. Standard diagnostic method currently being used is …

Non-invasive diagnostic potential of microRNA-203 in liquid biopsy of urothelial carcinoma of bladder

P Singh, A Singh, N Gupta, KD Raja, P Singh… - Molecular and Cellular …, 2022 - Springer
Increased CD44 antigen activity has been reported in recurrent cases of UBC. To date, no
reliable biomarker is available with high significance and specificity for non-invasive …

RAGE pathway activation and function in chronic kidney disease and COVID-19

CS Curran, JB Kopp - Frontiers in Medicine, 2022 - frontiersin.org
The multi-ligand receptor for advanced glycation end-products (RAGE) and its ligands are
contributing factors in autoimmunity, cancers, and infectious disease. RAGE activation is …

Diffuse proliferative glomerulonephritis in a patient with COVID-19 infection

VAG Flores, S Chicano, LP Resontoc… - BMJ Case Reports …, 2023 - casereports.bmj.com
COVID-19 primarily presents with respiratory involvement. Extrapulmonary manifestations
as the sole manifestation also occur although rare. The kidney, being one of the organs with …

Targeting mucin hypersecretion in COVID-19 therapy

P Prasher, M Sharma - Future Medicinal Chemistry, 2022 - Taylor & Francis
Conclusion The emergence of successive waves of COVID-19 prompted the identification of
novel approaches for effectively managing the further spread of the pandemic. Mucus …

[HTML][HTML] COVID-19 相关性肾损伤研究进展

谢娜, 李悦, 刘晓, 陆蕾, 朱慧敏… - Advances in Clinical …, 2023 - hanspub.org
自2019 年12 月发现新型冠状病毒肺炎(Corona Virus Disease 2019, COVID-19) 以来,
该病以其高传染性, 高致病率, 成为威胁全球的突发公共卫生事件. COVID-19 …