Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants

T Tamura, J Ito, K Uriu, J Zahradnik, I Kida… - Nature …, 2023 - nature.com
Abstract In late 2022, SARS-CoV-2 Omicron subvariants have become highly diversified,
and XBB is spreading rapidly around the world. Our phylogenetic analyses suggested that …

Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ. 1.1 variant

J Ito, R Suzuki, K Uriu, Y Itakura, J Zahradnik… - Nature …, 2023 - nature.com
In late 2022, various Omicron subvariants emerged and cocirculated worldwide. These
variants convergently acquired amino acid substitutions at critical residues in the spike …

[HTML][HTML] Virological characteristics of the SARS-CoV-2 BA. 2.86 variant

T Tamura, K Mizuma, H Nasser, S Deguchi… - Cell Host & Microbe, 2024 - cell.com
In late 2023, several SARS-CoV-2 XBB descendants, notably EG. 5.1, were predominant
worldwide. However, a distinct SARS-CoV-2 lineage, the BA. 2.86 variant, also emerged …

Virological characteristics of the SARS-CoV-2 Omicron XBB. 1.5 variant

T Tamura, T Irie, S Deguchi, H Yajima, M Tsuda… - Nature …, 2024 - nature.com
Abstract Circulation of SARS-CoV-2 Omicron XBB has resulted in the emergence of XBB.
1.5, a new Variant of Interest. Our phylogenetic analysis suggests that XBB. 1.5 evolved from …

Emergence of SARS‐CoV‐2 Omicron variant and strategies for tackling the infection

Y Wu, Y Long, F Wang, W Liu… - Immunity, Inflammation …, 2022 - Wiley Online Library
Abstract Introduction Nowadays, emerging SARS‐CoV‐2 Omicron, the novel highly mutated
VOC, has quickly spread as the dominant variant in over 190 countries worldwide through …

Molecular and structural insights into SARS-CoV-2 evolution: from BA. 2 to XBB subvariants

H Yajima, T Nomai, K Okumura, K Maenaka… - Mbio, 2024 - journals.asm.org
Due to the incessant emergence of various SARS-CoV-2 variants with enhanced fitness in
the human population, controlling the COVID-19 pandemic has been challenging …

An intranasal live-attenuated SARS-CoV-2 vaccine limits virus transmission

JM Adler, R Martin Vidal, C Langner… - Nature …, 2024 - nature.com
The development of effective SARS-CoV-2 vaccines has been essential to control COVID-
19, but significant challenges remain. One problem is intramuscular administration, which …

Multiple mutations of SARS-CoV-2 Omicron BA. 2 variant orchestrate its virological characteristics

I Kimura, D Yamasoba, H Nasser, H Ito… - Journal of …, 2023 - Am Soc Microbiol
Previous studies on the Omicron BA. 2 variant suggested that the virological characteristics
of BA. 2 are determined by the mutations in at least two different regions of the viral genome …

[HTML][HTML] Virological characteristics of the SARS-CoV-2 Omicron BA. 2.75 variant

A Saito, T Tamura, J Zahradnik, S Deguchi, K Tabata… - Cell host & …, 2022 - cell.com
Summary The SARS-CoV-2 Omicron BA. 2.75 variant emerged in May 2022. BA. 2.75 is a
BA. 2 descendant but is phylogenetically distinct from BA. 5, the currently predominant BA. 2 …

Virological characteristics of the SARS-CoV-2 Omicron EG. 5.1 variant

S Tsujino, S Deguchi, T Nomai, M Padilla-Blanco… - BioRxiv, 2023 - biorxiv.org
In middle-late 2023, a sublineage of SARS-CoV-2 Omicron XBB, EG. 5.1 (a progeny of XBB.
1.9. 2), is spreading rapidly around the world. Here, we performed multiscale investigations …