Long non-coding RNA and acute leukemia

GM Cruz-Miranda, A Hidalgo-Miranda… - International journal of …, 2019 - mdpi.com
Acute leukemia (AL) is the main type of cancer in children worldwide. Mortality by this
disease is high in developing countries and its etiology remains unanswered. Evidences …

Current research on non-coding ribonucleic acid (RNA)

J Wang, DC Samuels, S Zhao, Y Xiang, YY Zhao… - Genes, 2017 - mdpi.com
Non-coding ribonucleic acid (RNA) has without a doubt captured the interest of biomedical
researchers. The ability to screen the entire human genome with high-throughput …

HOTAIR beyond repression: In protein degradation, inflammation, DNA damage response, and cell signaling

RL Price, A Bhan, SS Mandal - DNA repair, 2021 - Elsevier
Long noncoding RNAs (lncRNAs) are pervasively transcribed from the mammalian genome
as transcripts that are usually> 200 nucleotides long. LncRNAs generally do not encode …

Long non-coding RNA signatures in Lymphopoiesis and lymphoid malignancies

H Baghdadi, R Heidari, M Zavvar, N Ahmadi… - Non-coding RNA, 2023 - mdpi.com
Lymphoid cells play a critical role in the immune system, which includes three subgroups of
T, B, and NK cells. Recognition of the complexity of the human genetics transcriptome in …

Linear and circular long non-coding RNAs in acute lymphoblastic leukemia: from pathogenesis to classification and treatment

Y Maimaitiyiming, L Ye, T Yang, W Yu… - International Journal of …, 2022 - mdpi.com
The coding regions account for only a small part of the human genome, and the remaining
vast majority of the regions generate large amounts of non-coding RNAs. Although non …

Drug resistance biomarkers and their clinical applications in childhood acute lymphoblastic leukemia

N Aberuyi, S Rahgozar, ES Ghodousi… - Frontiers in oncology, 2020 - frontiersin.org
Biomarkers are biological molecules found in body fluids or tissues, which can be
considered as indications of a normal or abnormal process, or of a condition or disease …

Transcriptome analysis identifies LINC00152 as a biomarker of early relapse and mortality in acute lymphoblastic leukemia

DA Bárcenas-López, JC Núñez-Enríquez… - Genes, 2020 - mdpi.com
Evidence showing the role of long non-coding RNAs (lncRNAs) in leukemogenesis have
emerged in the last decade. It has been proposed that these genes can be used as …

Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia

AR James, MP Schroeder, M Neumann… - Journal of Hematology & …, 2019 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) have emerged as a novel class of
RNA due to its diverse mechanism in cancer development and progression. However, the …

[HTML][HTML] Long noncoding RNA glutathione peroxidase 3–antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age …

Y Tu, L Li, B Qin, J Wu, T Cheng, L Kang… - Molecular vision, 2019 - ncbi.nlm.nih.gov
Purpose Age-related cataract (ARC) is the leading cause of visual impairment and blindness
worldwide. The apoptosis of lens epithelial cells (LECs) induced by oxidative damage is a …

Non-coding RNA signatures of B-cell acute lymphoblastic leukemia

PD Rodriguez, H Paculova, S Kogut, J Heath… - International Journal of …, 2021 - mdpi.com
Non-coding RNAs (ncRNAs) comprise a diverse class of non-protein coding transcripts that
regulate critical cellular processes associated with cancer. Advances in RNA-sequencing …